Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance V Adorno-Cruz, G Kibria, X Liu, M Doherty, DJ Junk, D Guan, C Hubert, ... Cancer research 75 (6), 924-929, 2015 | 261 | 2015 |
Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression JS Hale, B Otvos, M Sinyuk, AG Alvarado, M Hitomi, K Stoltz, Q Wu, ... Stem cells 32 (7), 1746-1758, 2014 | 248 | 2014 |
Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion B Otvos, DJ Silver, EE Mulkearns-Hubert, AG Alvarado, SM Turaga, ... Stem cells 34 (8), 2026-2039, 2016 | 242 | 2016 |
Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis TJ Alban, AG Alvarado, MD Sorensen, D Bayik, J Volovetz, E Serbinowski, ... JCI insight 3 (21), 2018 | 185 | 2018 |
Differential connexin function enhances self-renewal in glioblastoma M Hitomi, LP Deleyrolle, EE Mulkearns-Hubert, A Jarrar, M Li, M Sinyuk, ... Cell reports 11 (7), 1031-1042, 2015 | 126 | 2015 |
The intersection of cancer, cancer stem cells, and the immune system: therapeutic opportunities DJ Silver, M Sinyuk, MA Vogelbaum, MS Ahluwalia, JD Lathia Neuro-oncology 18 (2), 153-159, 2015 | 105 | 2015 |
Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats MJ Walters, K Ebsworth, RD Berahovich, MET Penfold, SC Liu, ... British journal of cancer 110 (5), 1179-1188, 2014 | 99 | 2014 |
Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation Y Gong, Y Ma, M Sinyuk, S Loganathan, RC Thompson, JN Sarkaria, ... Neuro-oncology 18 (1), 48-57, 2015 | 93 | 2015 |
High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor JD Lathia, M Li, M Sinyuk, AG Alvarado, WA Flavahan, K Stoltz, ... Cell reports 6 (1), 117-129, 2014 | 91 | 2014 |
Cancer connectors: connexins, gap junctions, and communication M Sinyuk, EE Mulkearns-Hubert, O Reizes, J Lathia Frontiers in oncology 8, 646, 2018 | 88 | 2018 |
Development of a fluorescent reporter system to delineate cancer stem cells in triple-negative breast cancer PS Thiagarajan, M Hitomi, JS Hale, AG Alvarado, B Otvos, M Sinyuk, ... Stem cells 33 (7), 2114-2125, 2015 | 86 | 2015 |
Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase PS Thiagarajan, M Sinyuk, SM Turaga, EE Mulkearns-Hubert, JS Hale, ... Nature communications 9 (1), 578, 2018 | 84 | 2018 |
Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling AG Alvarado, SM Turaga, P Sathyan, EE Mulkearns-Hubert, B Otvos, ... Neuro-oncology 18 (5), 656-666, 2016 | 41 | 2016 |
Context dependent role of the CD36-thrombospondin-histidine-rich glycoprotein axis in tumor angiogenesis and growth JS Hale, M Li, M Sinyuk, W Jahnen-Dechent, JD Lathia, RL Silverstein PloS one 7 (7), e40033, 2012 | 39 | 2012 |
The impact of regional astrocyte interferon-γ signaling during chronic autoimmunity: a novel role for the immunoproteasome BC Smith, M Sinyuk, JE Jenkins, MW Psenicka, JL Williams Journal of neuroinflammation 17, 1-14, 2020 | 33 | 2020 |
New advances and challenges of targeting cancer stem cells NK Dashzeveg, R Taftaf, EK Ramos, L Torre-Healy, A Chumakova, ... Cancer research 77 (19), 5222-5227, 2017 | 31 | 2017 |
Development of a Sox2 reporter system modeling cellular heterogeneity in glioma K Stoltz, M Sinyuk, JS Hale, Q Wu, B Otvos, K Walker, A Vasanji, JN Rich, ... Neuro-oncology 17 (3), 361-371, 2015 | 29 | 2015 |
Decoding the cancer stem cell hypothesis in glioblastoma JS Hale, M Sinyuk, JN Rich, JD Lathia CNS oncology 2 (4), 319-330, 2013 | 27 | 2013 |
Cx25 contributes to leukemia cell communication and chemosensitivity M Sinyuk, AG Alvarado, P Nesmiyanov, J Shaw, EE Mulkearns-Hubert, ... Oncotarget 6 (31), 31508, 2015 | 23 | 2015 |
Dissection and isolation of murine glia from multiple central nervous system regions M Sinyuk, JL Williams Journal of visualized experiments: JoVE, 2020 | 3 | 2020 |