Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 2754 | 2012 |
DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018 | 2514 | 2018 |
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer Cell 22 (4), 425-437, 2012 | 2020 | 2012 |
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer Cell 27 (5), 728-743, 2015 | 1153 | 2015 |
The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017 | 1041 | 2017 |
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012 | 982 | 2012 |
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ... Science 355 (6332), eaai8478, 2017 | 924 | 2017 |
New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 885 | 2016 |
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ... Cell 176 (6), 1265-1281. e24, 2019 | 858 | 2019 |
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013 | 842 | 2013 |
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ... Cancer cell 25 (3), 393-405, 2014 | 835 | 2014 |
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ... Cancer cell 24 (5), 660-672, 2013 | 800 | 2013 |
DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis F Sahm, D Schrimpf, D Stichel, DTW Jones, T Hielscher, S Schefzyk, ... The Lancet Oncology 18 (5), 682-694, 2017 | 777 | 2017 |
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 717 | 2014 |
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 661 | 2014 |
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ... Science 360 (6386), 331-335, 2018 | 607 | 2018 |
Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ... Cancer cell 29 (3), 379-393, 2016 | 553 | 2016 |
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma … DE Reuss, F Sahm, D Schrimpf, B Wiestler, D Capper, C Koelsche, ... Acta neuropathologica 129 (1), 133-146, 2015 | 514 | 2015 |
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. J Richter, M Schlesner, S Hoffmann, M Kreuz, E Leich, B Burkhardt, ... Nature genetics, 2012 | 500 | 2012 |
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing JK Nuñez, J Chen, GC Pommier, JZ Cogan, JM Replogle, C Adriaens, ... Cell 184 (9), 2503-2519. e17, 2021 | 491 | 2021 |