Follow
Jun Wang
Title
Cited by
Cited by
Year
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
C Ma, MD Sacco, B Hurst, JA Townsend, Y Hu, T Szeto, X Zhang, ...
Cell research 30 (8), 678-692, 2020
7252020
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
SD Cady, K Schmidt-Rohr, J Wang, CS Soto, WF DeGrado, M Hong
Nature 463 (7281), 689-692, 2010
7002010
Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against Mpro and cathepsin L
MD Sacco, C Ma, P Lagarias, A Gao, JA Townsend, X Meng, P Dube, ...
Science Advances 6 (50), eabe0751, 2020
3252020
Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus
J Wang, Y Wu, C Ma, G Fiorin, J Wang, LH Pinto, RA Lamb, ML Klein, ...
Proceedings of the National Academy of Sciences 110 (4), 1315-1320, 2013
2492013
Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are nonspecific promiscuous SARS-CoV-2 main protease inhibitors
C Ma, Y Hu, JA Townsend, PI Lagarias, MT Marty, A Kolocouris, J Wang
ACS pharmacology & translational science 3 (6), 1265-1277, 2020
2052020
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
B Boras, RM Jones, BJ Anson, D Arenson, L Aschenbrenner, ...
Nature communications 12 (1), 6055, 2021
1852021
Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2
J Wang, C Ma, G Fiorin, V Carnevale, T Wang, F Hu, RA Lamb, LH Pinto, ...
Journal of the American Chemical Society 133 (32), 12834-12841, 2011
1582011
Protein and small molecule microarrays: powerful tools for high-throughput proteomics
M Uttamchandani, J Wang, SQ Yao
Molecular Biosystems 2 (1), 58-68, 2006
1562006
Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission
NW Schmidt, A Mishra, J Wang, WF DeGrado, GCL Wong
Journal of the American Chemical Society 135 (37), 13710-13719, 2013
1502013
The in vitro antiviral activity of lactoferrin against common human coronaviruses and SARS-CoV-2 is mediated by targeting the heparan sulfate co-receptor
Y Hu, X Meng, F Zhang, Y Xiang, J Wang
Emerging microbes & infections 10 (1), 317-330, 2021
1482021
Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus
J Wang, JX Qiu, C Soto, WF DeGrado
Current opinion in structural biology 21 (1), 68-80, 2011
1432011
Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine …
SD Cady, J Wang, Y Wu, WF DeGrado, M Hong
Journal of the American Chemical Society 133 (12), 4274-4284, 2011
1212011
Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus
V Balannik, J Wang, Y Ohigashi, X Jing, E Magavern, RA Lamb, ...
Biochemistry 48 (50), 11872-11882, 2009
1202009
Naturally occurring mutations of SARS-CoV-2 main protease confer drug resistance to nirmatrelvir
Y Hu, EM Lewandowski, H Tan, X Zhang, RT Morgan, X Zhang, ...
ACS central science 9 (8), 1658-1669, 2023
1172023
Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus
J Wang, C Ma, J Wang, H Jo, B Canturk, G Fiorin, LH Pinto, RA Lamb, ...
Journal of medicinal chemistry 56 (7), 2804-2812, 2013
1162013
Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and a FlipGFP-based reporter assay
C Ma, MD Sacco, Z Xia, G Lambrinidis, JA Townsend, Y Hu, X Meng, ...
ACS central science 7 (7), 1245-1260, 2021
1142021
Expedited approach toward the rational design of noncovalent SARS-CoV-2 main protease inhibitors
N Kitamura, MD Sacco, C Ma, Y Hu, JA Townsend, X Meng, F Zhang, ...
Journal of medicinal chemistry 65 (4), 2848-2865, 2021
1122021
Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus
J Wang, SD Cady, V Balannik, LH Pinto, WF DeGrado, M Hong
Journal of the American Chemical Society 131 (23), 8066-8076, 2009
1092009
Discovery of a novel inhibitor of coronavirus 3CL protease for the potential treatment of COVID-19
B Boras, RM Jones, BJ Anson, D Arenson, L Aschenbrenner, ...
BioRxiv, 2020.09. 12.293498, 2020
1062020
Inhibitors of the M2 proton channel engage and disrupt transmembrane networks of hydrogen-bonded waters
JL Thomaston, NF Polizzi, A Konstantinidi, J Wang, A Kolocouris, ...
Journal of the American Chemical Society 140 (45), 15219-15226, 2018
1052018
The system can't perform the operation now. Try again later.
Articles 1–20