Molecular subgroups of medulloblastoma: the current consensus MD Taylor, PA Northcott, A Korshunov, M Remke, YJ Cho, SC Clifford, ... Acta neuropathologica 123, 465-472, 2012 | 2163 | 2012 |
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ... Acta neuropathologica 123, 473-484, 2012 | 1176 | 2012 |
Intertumoral heterogeneity within medulloblastoma subgroups FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ... Cancer cell 31 (6), 737-754. e6, 2017 | 1155 | 2017 |
Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 1008 | 2012 |
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012 | 984 | 2012 |
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ... Cell 148 (1), 59-71, 2012 | 974 | 2012 |
New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 901 | 2016 |
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ... Cancer cell 25 (3), 393-405, 2014 | 839 | 2014 |
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 725 | 2014 |
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 669 | 2014 |
Risk stratification of childhood medulloblastoma in the molecular era: the current consensus V Ramaswamy, M Remke, E Bouffet, S Bailey, SC Clifford, F Doz, M Kool, ... Acta neuropathologica 131, 821-831, 2016 | 663 | 2016 |
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas S Pfister, WG Janzarik, M Remke, A Ernst, W Werft, N Becker, G Toedt, ... The Journal of clinical investigation 118 (5), 1739-1749, 2008 | 594 | 2008 |
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma H Witt, SC Mack, M Ryzhova, S Bender, M Sill, R Isserlin, A Benner, ... Cancer cell 20 (2), 143-157, 2011 | 582 | 2011 |
Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ... Journal of Clinical Oncology 31 (23), 2927-2935, 2013 | 539 | 2013 |
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ... Cell 153 (5), 1064-1079, 2013 | 455 | 2013 |
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples PA Northcott, DJH Shih, M Remke, YJ Cho, M Kool, C Hawkins, ... Acta neuropathologica 123, 615-626, 2012 | 440 | 2012 |
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis V Ramaswamy, M Remke, E Bouffet, CC Faria, S Perreault, YJ Cho, ... The lancet oncology 14 (12), 1200-1207, 2013 | 418 | 2013 |
Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors S Gholamin, SS Mitra, AH Feroze, J Liu, SA Kahn, M Zhang, R Esparza, ... Science translational medicine 9 (381), eaaf2968, 2017 | 403 | 2017 |
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ... Nature genetics 47 (3), 257-262, 2015 | 399 | 2015 |
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis EM Thompson, T Hielscher, E Bouffet, M Remke, B Luu, S Gururangan, ... The lancet oncology 17 (4), 484-495, 2016 | 393 | 2016 |