Javier sancho

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Adrian Velazquez-CampoyInstitute BIFI – University of ZaragozaVerified email at unizar.es
Juan José Galano FrutosPh. D. in Biochemistry and Molecular Biology, University of ZaragozaVerified email at unizar.es
Alan FershtEmeritus Group Leader, MRC Laboratory of Molecular Biology, University of CambridgeVerified email at cam.ac.uk
Marta BuenoPulmonary and Critical Care Medicine, University of PittsburghVerified email at pitt.edu
Salvador VenturaInstitute of Biotechnology and Biomedicine (IBB), Universitat Autonoma de BarcelonaVerified email at uab.es
Anabel LostaoInstituto de Nanociencia y Materiales de Aragón (INMA). Universidad de Zaragoza. Fundación ARAIDVerified email at unizar.es
Vladimir Espinosa AngaricaSenior Research Fellow at DUKE-NUS Medical School, National University of SingaporeVerified email at duke-nus.edu.sg
Angel LanasUniversity of Zaragoza. University Clinic Hospital. IIS Aragón. CiberehdVerified email at unizar.es
Juan Fernandez-RecioInstituto de Ciencias de la Vid y del Vino (ICVV), CSIC / Uni. Rioja / Gob. RiojaVerified email at icvv.es
Andrés González RodríguezUniversity of ZaragozaVerified email at unizar.es
M. Ángeles JiménezInstituto de Química Física Blas Cabrera (IQF, CSIC)Verified email at iqfr.csic.es
CLAUDIA MACHICADO RIVEROHead, Lab. of Translational Research and Computational Biology, Universidad Peruana Cayetano HerediaVerified email at upch.pe
Fernando FaloFísica de la Materia Condensada y BIFI, Universidad de ZaragozaVerified email at unizar.es
Aurora MartinezProfessor ved University of BergenVerified email at uib.no
Sonia VegaInstitute BIFI - University of ZaragozaVerified email at bifi.es
Jose M. Sanchez-RuizUniversidad de Granada (Spain)Verified email at ugr.es
Carmen M. RomeroDepartamento de Química, Universidad Nacional de ColombiaVerified email at unal.edu.co
Angel Luis PeyAssociate Professor, Department of Physical Chemistry, Universidad de Granada (Spain)Verified email at ugr.es
Beat ThönyProfessor of Clincial Biochemistry, Department of Pediatrics, University of Zürich, SwitzerlandVerified email at kispi.uzh.ch
Dale EdmondsonProfessor of Biochemistry, Emory UniversityVerified email at emory.edu

Javier sancho

professor of biochemistry, universidad de zaragoza

Verified email at unizar.es


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Effect of alanine versus glycine in α-helices on protein stability L Serrano, JL Neira, J Sancho, AR Fersht Nature Publishing Group 356 (6368), 453-455, 1992	273	1992
Histidine-aromatic interactions in barnase: Elevation of histidine pKa and contribution to protein stability R Loewenthal, J Sancho, AR Fersht Journal of molecular biology 224 (3), 759-770, 1992	272	1992
α-Helix stability in proteins: I. Empirical correlations concerning substitution of side-chains at the N and C-caps and the replacement of alanine by glycine or serine at … L Serrano, J Sancho, M Hirshberg, AR Fersht Journal of molecular biology 227 (2), 544-559, 1992	265	1992
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons J Pujols, S Peña-Díaz, DF Lázaro, F Peccati, F Pinheiro, D González, ... Proceedings of the National Academy of Sciences 115 (41), 10481-10486, 2018	232	2018
Flavodoxins: sequence, folding, binding, function and beyond J Sancho Cellular and Molecular Life Sciences CMLS 63 (7-8), 855-864, 2006	223	2006
Circular dichroism studies of barnase and its mutants: characterization of the contribution of aromatic side chains S Vuilleumier, J Sancho, R Loewenthal, AR Fersht Biochemistry 32 (39), 10303-10313, 1993	207	1993
Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria AL Pey, M Ying, N Cremades, A Velazquez-Campoy, T Scherer, B Thöny, ... The Journal of clinical investigation 118 (8), 2858-2867, 2008	199	2008
Fluorescence spectrum of barnase: contributions of three tryptophan residues and a histidine-related pH dependence R Loewenthal, J Sancho, AR Fersht Biochemistry 30 (27), 6775-6779, 1991	176	1991
Histidine residues at the N-and C-termini of alpha-helices: perturbed pKas and protein stability. J Sancho, L Serrano, AR Fersht Biochemistry 31 (8), 2253-2258, 1992	167	1992
Miglustat (NB-DNJ) works as a chaperone for mutated acid β-glucosidase in cells transfected with several Gaucher disease mutations P Alfonso, S Pampín, J Estrada, JC Rodríguez-Rey, P Giraldo, J Sancho, ... Blood Cells, Molecules, and Diseases 35 (2), 268-276, 2005	162	2005
The tryptophan/histidine interaction in α-helices J Fernández-Recio, A Vázquez, C Civera, P Sevilla, J Sancho Journal of molecular biology 267 (1), 184-197, 1997	125	1997
The active site of pepsin is formed in the intermediate conformation dominant at mildly acidic pH LA Campos, J Sancho FEBS letters 538 (1-3), 89-95, 2003	122	2003
Differential stabilization of the three FMN redox forms by tyrosine 94 and tryptophan 57 in flavodoxin from Anabaena and its influence on the redox potentials A Lostao, C Gómez-Moreno, SG Mayhew, J Sancho Biochemistry 36 (47), 14334-14344, 1997	119	1997
Long-range surface charge-charge interactions in proteins: comparison of experimental results with calculations from a theoretical method R Loewenthal, J Sancho, T Reinikainen, AR Fersht Journal of molecular biology 232 (2), 574-583, 1993	111	1993
An N-terminal fragment of barnase has residual helical structure similar to that in a refolding intermediate J Sancho, JL Neira, AR Fersht Journal of molecular biology 224 (3), 749-758, 1992	108	1992
ProtSA: a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble J Estrada, P Bernadó, M Blackledge, J Sancho BMC bioinformatics 10 (1), 1, 2009	105	2009
Closure of a tyrosine/tryptophan aromatic gate leads to a compact fold in apo flavodoxin CG Genzor, A Perales-Alcón, J Sancho, A Romero Nature Structural Biology 3 (4), 329-332, 1996	103	1996
Dissection of an enzyme by protein engineering: the N and C-terminal fragments of barnase form a native-like complex with restored enzymic activity J Sancho, AR Fersht Journal of molecular biology 224 (3), 741-747, 1992	103	1992
Folding of barnase in parts AD Kippen, J Sancho, AR Fersht Biochemistry 33 (12), 3778-3786, 1994	99	1994
An intragenic suppressor in the cytochrome c oxidase I gene of mouse mitochondrial DNA R Acín-Pérez, MP Bayona-Bafaluy, M Bueno, C Machicado, ... Human molecular genetics 12 (3), 329-339, 2003	98	2003

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