Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... nature 500 (7463), 415-421, 2013 | 10203 | 2013 |
Complex heatmaps reveal patterns and correlations in multidimensional genomic data Z Gu, R Eils, M Schlesner Bioinformatics 32 (18), 2847-2849, 2016 | 7025 | 2016 |
" Circlize" implements and enhances circular visualization in R Z Gu, L Gu, R Eils, M Schlesner, B Brors | 3202 | 2014 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1852* | 2020 |
The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 1381 | 2018 |
The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017 | 1010 | 2017 |
The evolutionary history of 2,658 cancers M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ... Nature 578 (7793), 122-128, 2020 | 942 | 2020 |
New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 858 | 2016 |
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013 | 829 | 2013 |
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing Nature genetics 44 (12), 1316-1320, 2012 | 496 | 2012 |
Computational pan-genomics: status, promises and challenges Briefings in bioinformatics 19 (1), 118-135, 2018 | 345 | 2018 |
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... Cell 184 (8), 2239-2254. e39, 2021 | 336 | 2021 |
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing TS Alioto, I Buchhalter, S Derdak, B Hutter, MD Eldridge, E Hovig, ... Nature communications 6 (1), 1-13, 2015 | 333 | 2015 |
Next-generation personalised medicine for high-risk paediatric cancer patients–The INFORM pilot study BC Worst, CM van Tilburg, GP Balasubramanian, P Fiesel, R Witt, ... European journal of cancer 65, 91-101, 2016 | 328 | 2016 |
Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories C Gerhauser, F Favero, T Risch, R Simon, L Feuerbach, Y Assenov, ... Cancer cell 34 (6), 996-1011. e8, 2018 | 251 | 2018 |
Integrative genomic and transcriptomic analysis of leiomyosarcoma P Chudasama, SS Mughal, MA Sanders, D Hübschmann, I Chung, ... Nature communications 9 (1), 144, 2018 | 251 | 2018 |
Evolutionary trajectories of IDHWT glioblastomas reveal a common path of early tumorigenesis instigated years ahead of initial diagnosis V Körber, J Yang, P Barah, Y Wu, D Stichel, Z Gu, MNC Fletcher, D Jones, ... Cancer cell 35 (4), 692-704. e12, 2019 | 240 | 2019 |
The mutational pattern of primary lymphoma of the central nervous system determined by whole-exome sequencing I Vater, M Montesinos-Rongen, M Schlesner, A Haake, F Purschke, ... Leukemia 29 (3), 677-685, 2015 | 237 | 2015 |
NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer C Heining, P Horak, S Uhrig, PL Codo, B Klink, B Hutter, M Fröhlich, ... Cancer discovery 8 (9), 1087-1095, 2018 | 228 | 2018 |
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma EM Noll, C Eisen, A Stenzinger, E Espinet, A Muckenhuber, C Klein, ... Nature medicine 22 (3), 278-287, 2016 | 223 | 2016 |