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Stephen Mack
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Cancer stem cells in glioblastoma
JD Lathia, SC Mack, EE Mulkearns-Hubert, CLL Valentim, JN Rich
Genes & development 29 (12), 1203-1217, 2015
17262015
Medulloblastoma comprises four distinct molecular variants
PA Northcott, A Korshunov, H Witt, T Hielscher, CG Eberhart, S Mack, ...
Journal of clinical oncology 29 (11), 1408-1414, 2011
15792011
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups
KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ...
Cancer cell 27 (5), 728-743, 2015
11562015
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ...
Nature 488 (7409), 49-56, 2012
10002012
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
6632014
A three-dimensional organoid culture system derived from human glioblastomas recapitulates the hypoxic gradients and cancer stem cell heterogeneity of tumors found in vivo
CG Hubert, M Rivera, LC Spangler, Q Wu, SC Mack, BC Prager, M Couce, ...
Cancer research 76 (8), 2465-2477, 2016
6182016
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma
H Witt, SC Mack, M Ryzhova, S Bender, M Sill, R Isserlin, A Benner, ...
Cancer cell 20 (2), 143-157, 2011
5792011
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison, S Croul, S Mack, ...
Nature genetics 41 (4), 465-472, 2009
5012009
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ...
Nature 572 (7767), 67-73, 2019
4052019
Cross-species genomics matches driver mutations and cell compartments to model ependymoma
RA Johnson, KD Wright, H Poppleton, KM Mohankumar, D Finkelstein, ...
Nature 466 (7306), 632-636, 2010
4002010
Cytogenetic prognostication within medulloblastoma subgroups
DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ...
Journal of clinical oncology 32 (9), 886-896, 2014
3722014
Targeting glioma stem cells through combined BMI1 and EZH2 inhibition
X Jin, LJY Kim, Q Wu, LC Wallace, BC Prager, T Sanvoranart, RC Gimple, ...
Nature medicine 23 (11), 1352-1361, 2017
3582017
Divergent clonal selection dominates medulloblastoma at recurrence
AS Morrissy, L Garzia, DJH Shih, S Zuyderduyn, X Huang, P Skowron, ...
Nature 529 (7586), 351-357, 2016
3552016
The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants
KW Pajtler, SC Mack, V Ramaswamy, CA Smith, H Witt, A Smith, ...
Acta neuropathologica 133, 5-12, 2017
3292017
Preferential iron trafficking characterizes glioblastoma stem-like cells
DL Schonberg, TE Miller, Q Wu, WA Flavahan, NK Das, JS Hale, ...
Cancer cell 28 (4), 441-455, 2015
3142015
Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study
P Castelo-Branco, S Choufani, S Mack, D Gallagher, C Zhang, T Lipman, ...
The lancet oncology 14 (6), 534-542, 2013
3002013
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
PA Northcott, T Hielscher, A Dubuc, S Mack, D Shih, M Remke, ...
Acta neuropathologica 122, 231-240, 2011
2862011
Functional enhancers shape extrachromosomal oncogene amplifications
AR Morton, N Dogan-Artun, ZJ Faber, G MacLeod, CF Bartels, MS Piazza, ...
Cell 179 (6), 1330-1341. e13, 2019
2812019
N6-methyladenine DNA modification in glioblastoma
Q Xie, TP Wu, RC Gimple, Z Li, BC Prager, Q Wu, Y Yu, P Wang, Y Wang, ...
Cell 175 (5), 1228-1243. e20, 2018
2762018
AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells
S Pei, M Minhajuddin, B Adane, N Khan, BM Stevens, SC Mack, S Lai, ...
Cell stem cell 23 (1), 86-100. e6, 2018
2532018
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