Daniel Rosenbaum
Daniel Rosenbaum
Professor of Biophysics, UT Southwestern
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High-resolution crystal structure of an engineered human β2-adrenergic G protein–coupled receptor
V Cherezov, DM Rosenbaum, MA Hanson, SGF Rasmussen, FS Thian, ...
science 318 (5854), 1258-1265, 2007
The structure and function of G-protein-coupled receptors
DM Rosenbaum, SGF Rasmussen, BK Kobilka
Nature 459 (7245), 356-363, 2009
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
SGF Rasmussen, HJ Choi, DM Rosenbaum, TS Kobilka, FS Thian, ...
Nature 450 (7168), 383-387, 2007
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
SGF Rasmussen, HJ Choi, JJ Fung, E Pardon, P Casarosa, PS Chae, ...
Nature 469 (7329), 175-180, 2011
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
DM Rosenbaum, V Cherezov, MA Hanson, SGF Rasmussen, FS Thian, ...
science 318 (5854), 1266-1273, 2007
Structure and dynamics of the M3 muscarinic acetylcholine receptor
AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ...
Nature 482 (7386), 552-556, 2012
Structure and function of an irreversible agonist-β2 adrenoceptor complex
DM Rosenbaum, C Zhang, JA Lyons, R Holl, D Aragao, DH Arlow, ...
Nature 469 (7329), 236-240, 2011
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
MP Bokoch, Y Zou, SGF Rasmussen, CW Liu, R Nygaard, ...
Nature 463 (7277), 108-112, 2010
High-resolution crystal structure of the human CB1 cannabinoid receptor
Z Shao, J Yin, K Chapman, M Grzemska, L Clark, J Wang, ...
Nature 540 (7634), 602-606, 2016
Structure-based discovery of β2-adrenergic receptor ligands
P Kolb, DM Rosenbaum, JJ Irwin, JJ Fung, BK Kobilka, BK Shoichet
Proceedings of the National Academy of Sciences 106 (16), 6843-6848, 2009
Insulin resistance in polycystic ovary syndrome: decreased expression of GLUT-4 glucose transporters in adipocytes
D Rosenbaum, RS Haber, A Dunaif
American Journal of Physiology-Endocrinology and Metabolism 264 (2), E197-E202, 1993
Crystal structure of the human sterol transporter ABCG5/ABCG8
JY Lee, LN Kinch, DM Borek, J Wang, J Wang, IL Urbatsch, XS Xie, ...
Nature 533 (7604), 561-564, 2016
Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant
J Yin, JC Mobarec, P Kolb, DM Rosenbaum
Nature 519 (7542), 247-250, 2015
Structural and functional diversity calls for a new classification of ABC transporters
C Thomas, SG Aller, K Beis, EP Carpenter, G Chang, L Chen, E Dassa, ...
FEBS letters 594 (23), 3767-3775, 2020
Efficient and sequence-specific DNA-templated polymerization of peptide nucleic acid aldehydes
DM Rosenbaum, DR Liu
Journal of the American Chemical Society 125 (46), 13924-13925, 2003
Structure of a D2 dopamine receptor–G-protein complex in a lipid membrane
J Yin, KYM Chen, MJ Clark, M Hijazi, P Kumari, X Bai, RK Sunahara, ...
Nature 584 (7819), 125-129, 2020
Structure of an allosteric modulator bound to the CB1 cannabinoid receptor
Z Shao, W Yan, K Chapman, K Ramesh, AJ Ferrell, J Yin, X Wang, Q Xu, ...
Nature chemical biology 15 (12), 1199-1205, 2019
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors
J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ...
Nature Structural & Molecular Biology 23 (4), 293-299, 2016
Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes
P Xiao, W Yan, L Gou, YN Zhong, L Kong, C Wu, X Wen, Y Yuan, S Cao, ...
Cell 184 (4), 943-956. e18, 2021
Ligand modulation of sidechain dynamics in a wild-type human GPCR
LD Clark, I Dikiy, K Chapman, KEJ Rödström, J Aramini, MV LeVine, ...
Elife 6, e28505, 2017
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