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Douglas Gladue
Douglas Gladue
Senior Scientist, Agricultural Research Service at Plum Island Animal Disease Center
Verified email at usda.gov - Homepage
Title
Cited by
Cited by
Year
African swine fever virus Georgia isolate harboring deletions of MGF360 and MGF505 genes is attenuated in swine and confers protection against challenge with virulent parental …
V O'Donnell, LG Holinka, DP Gladue, B Sanford, PW Krug, X Lu, J Arzt, ...
Journal of virology 89 (11), 6048-6056, 2015
3012015
Development of a highly effective African swine fever virus vaccine by deletion of the I177L gene results in sterile immunity against the current epidemic Eurasia strain
MV Borca, E Ramirez-Medina, E Silva, E Vuono, A Rai, S Pruitt, ...
Journal of virology 94 (7), 10.1128/jvi. 02017-19, 2020
2612020
DEP-domain-mediated regulation of GPCR signaling responses
DR Ballon, PL Flanary, DP Gladue, JB Konopka, HG Dohlman, J Thorner
Cell 126 (6), 1079-1093, 2006
2272006
Simultaneous Deletion of the 9GL and UK Genes from the African Swine Fever Virus Georgia 2007 Isolate Offers Increased Safety and Protection against …
V O'Donnell, GR Risatti, LG Holinka, PW Krug, J Carlson, ...
Journal of virology 91 (1), 10.1128/jvi. 01760-16, 2017
2162017
African Swine Fever Virus Georgia 2007 with a Deletion of Virulence-Associated Gene 9GL (B119L), when Administered at Low Doses, Leads to Virus Attenuation …
V O'Donnell, LG Holinka, PW Krug, DP Gladue, J Carlson, B Sanford, ...
Journal of virology 89 (16), 8556-8566, 2015
1792015
The progressive adaptation of a georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major …
PW Krug, LG Holinka, V O'Donnell, B Reese, B Sanford, ...
Journal of virology 89 (4), 2324-2332, 2015
1622015
African swine fever virus Georgia isolate harboring deletions of 9GL and MGF360/505 genes is highly attenuated in swine but does not confer protection against parental virus …
V O’Donnell, LG Holinka, B Sanford, PW Krug, J Carlson, JM Pacheco, ...
Virus research 221, 8-14, 2016
1362016
Positive selection of ORF1ab, ORF3a, and ORF8 genes drives the early evolutionary trends of SARS-CoV-2 during the 2020 COVID-19 pandemic
L Velazquez-Salinas, S Zarate, S Eberl, DP Gladue, I Novella, MV Borca
Frontiers in microbiology 11, 550674, 2020
1322020
Foot-and-mouth disease virus nonstructural protein 2C interacts with Beclin1, modulating virus replication
DP Gladue, V O'Donnell, R Baker-Branstetter, LG Holinka, JM Pacheco, ...
Journal of virology 86 (22), 12080-12090, 2012
1112012
ASFV-G-∆ I177L as an effective oral nasal vaccine against the Eurasia strain of Africa swine fever
MV Borca, E Ramirez-Medina, E Silva, E Vuono, A Rai, S Pruitt, ...
Viruses 13 (5), 765, 2021
932021
African swine fever virus vaccine candidate ASFV‐G‐ΔI177L efficiently protects European and native pig breeds against circulating Vietnamese field strain
XH Tran, TTP Le, QH Nguyen, TT Do, VD Nguyen, CG Gay, MV Borca, ...
Transboundary and Emerging Diseases 69 (4), e497-e504, 2022
922022
Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine
MV Borca, V o’Donnell, LG Holinka, GR Risatti, E Ramirez-Medina, ...
Scientific reports 10 (1), 494, 2020
852020
A cell culture-adapted vaccine virus against the current African swine fever virus pandemic strain
MV Borca, A Rai, E Ramirez-Medina, E Silva, L Velazquez-Salinas, ...
Journal of virology 95 (14), 10.1128/jvi. 00123-21, 2021
842021
Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages
JJ Zhu, P Ramanathan, EA Bishop, V O’Donnell, DP Gladue, MV Borca
PloS one 14 (11), e0223955, 2019
842019
Deletion of the thymidine kinase gene induces complete attenuation of the Georgia isolate of African swine fever virus
B Sanford, LG Holinka, V O'donnell, PW Krug, J Carlson, M Alfano, ...
Virus research 213, 165-171, 2016
842016
Association of the host immune response with protection using a live attenuated African swine fever virus model
J Carlson, V O’Donnell, M Alfano, L Velazquez Salinas, LG Holinka, ...
Viruses 8 (10), 291, 2016
832016
CRISPR-Cas9, a tool to efficiently increase the development of recombinant African swine fever viruses
MV Borca, LG Holinka, KA Berggren, DP Gladue
Scientific reports 8 (1), 3154, 2018
792018
Classical swine fever virus p7 protein is a viroporin involved in virulence in swine
DP Gladue, LG Holinka, E Largo, I Fernandez Sainz, C Carrillo, ...
Journal of virology 86 (12), 6778-6791, 2012
792012
Deletion of the A137R gene from the pandemic strain of African swine fever virus attenuates the strain and offers protection against the virulent pandemic virus
DP Gladue, E Ramirez-Medina, E Vuono, E Silva, A Rai, S Pruitt, ...
Journal of virology 95 (21), 10.1128/jvi. 01139-21, 2021
752021
Foot-and-mouth disease virus modulates cellular vimentin for virus survival
DP Gladue, V O'donnell, R Baker-Branstetter, LG Holinka, JM Pacheco, ...
Journal of virology 87 (12), 6794-6803, 2013
672013
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