Structure and function of TolC: the bacterial exit duct for proteins and drugs V Koronakis, J Eswaran, C Hughes Annual review of biochemistry 73 (1), 467-489, 2004 | 450 | 2004 |
Interactions underlying assembly of the Escherichia coli AcrAB–TolC multidrug efflux system T Touzé, J Eswaran, E Bokma, E Koronakis, C Hughes, V Koronakis Molecular microbiology 53 (2), 697-706, 2004 | 289 | 2004 |
RNA sequencing of cancer reveals novel splicing alterations J Eswaran, A Horvath, S Godbole, SD Reddy, P Mudvari, K Ohshiro, ... Scientific reports 3 (1), 1-12, 2013 | 228 | 2013 |
Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site ED Scheeff, J Eswaran, G Bunkoczi, S Knapp, G Manning Structure 17 (1), 128-138, 2009 | 218 | 2009 |
Transition to the open state of the TolC periplasmic tunnel entrance C Andersen, E Koronakis, E Bokma, J Eswaran, D Humphreys, C Hughes, ... Proceedings of the National Academy of Sciences 99 (17), 11103-11108, 2002 | 212 | 2002 |
Three's company: component structures bring a closer view of tripartite drug efflux pumps J Eswaran, E Koronakis, MK Higgins, C Hughes, V Koronakis Current opinion in structural biology 14 (6), 741-747, 2004 | 208 | 2004 |
Structure and functional characterization of the atypical human kinase haspin J Eswaran, D Patnaik, P Filippakopoulos, F Wang, RL Stein, JW Murray, ... Proceedings of the National Academy of Sciences 106 (48), 20198-20203, 2009 | 176 | 2009 |
Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition M Soundararajan, AK Roos, P Savitsky, P Filippakopoulos, ... Structure 21 (6), 986-996, 2013 | 174 | 2013 |
UnPAKing the class differences among p21-activated kinases J Eswaran, M Soundararajan, R Kumar, S Knapp Trends in biochemical sciences 33 (8), 394-403, 2008 | 159 | 2008 |
Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs J Eswaran, WH Lee, JÉ Debreczeni, P Filippakopoulos, A Turnbull, ... Structure 15 (2), 201-213, 2007 | 142 | 2007 |
Metastasis-associated protein 1/nucleosome remodeling and histone deacetylase complex in cancer DQ Li, SB Pakala, SS Nair, J Eswaran, R Kumar Cancer research 72 (2), 387-394, 2012 | 139 | 2012 |
MORC2 signaling integrates phosphorylation-dependent, ATPase-coupled chromatin remodeling during the DNA damage response DQ Li, SS Nair, K Ohshiro, A Kumar, VS Nair, SB Pakala, SDN Reddy, ... Cell reports 2 (6), 1657-1669, 2012 | 138 | 2012 |
Transcriptomic landscape of breast cancers through mRNA sequencing J Eswaran, D Cyanam, P Mudvari, SDN Reddy, SB Pakala, SS Nair, ... Scientific reports 2 (1), 264, 2012 | 117 | 2012 |
Self‐association of EPEC intimin mediated by the β‐barrel‐containing anchor domain: a role in clustering of the Tir receptor T Touzé, RD Hayward, J Eswaran, JM Leong, V Koronakis Molecular microbiology 51 (1), 73-87, 2004 | 109 | 2004 |
Targeting group II PAKs in cancer and metastasis J Eswaran, M Soundararajan, S Knapp Cancer and Metastasis Reviews 28, 209-217, 2009 | 99 | 2009 |
Molecular pathways: targeting p21-activated kinase 1 signaling in cancer—opportunities, challenges, and limitations J Eswaran, DQ Li, A Shah, R Kumar Clinical Cancer Research 18 (14), 3743-3749, 2012 | 94 | 2012 |
Locking TolC entrance helices to prevent protein translocation by the bacterial type I export apparatus J Eswaran, C Hughes, V Koronakis Journal of molecular biology 327 (2), 309-315, 2003 | 79 | 2003 |
Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases J Eswaran, JP von Kries, B Marsden, E Longman, JÉ Debreczeni, ... Biochemical Journal 395 (3), 483-491, 2006 | 77 | 2006 |
Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug efflux protein TolC MK Higgins, J Eswaran, P Edwards, GFX Schertler, C Hughes, ... Journal of molecular biology 342 (3), 697-702, 2004 | 76 | 2004 |
Insights into protein kinase regulation and inhibition by large scale structural comparison J Eswaran, S Knapp Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 429-432, 2010 | 68 | 2010 |