P. John Hart
P. John Hart
Ewing Halsell/President's Council Distinguished Chair in Biochemistry
Verified email at - Homepage
Cited by
Cited by
Misfolded CuZnSOD and amyotrophic lateral sclerosis
JS Valentine, PJ Hart
Proceedings of the National Academy of Sciences 100 (7), 3617-3622, 2003
Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS
JS Elam, AB Taylor, R Strange, S Antonyuk, PA Doucette, JA Rodriguez, ...
Nature Structural & Molecular Biology 10 (6), 461-467, 2003
Crystal structure of the human TβR2 ectodomain–TGF-β3 complex
PJ Hart, S Deep, AB Taylor, Z Shu, CS Hinck, AP Hinck
Nature structural biology 9 (3), 203-208, 2002
Sequence-specific recognition and cooperative dimerization of N-terminal aromatic peptides in aqueous solution by a synthetic host
LM Heitmann, AB Taylor, PJ Hart, AR Urbach
Journal of the American Chemical Society 128 (38), 12574-12581, 2006
Molecular recognition of insulin by a synthetic receptor
JM Chinai, AB Taylor, LM Ryno, ND Hargreaves, CA Morris, PJ Hart, ...
Journal of the American Chemical Society 133 (23), 8810-8813, 2011
A Structure-Based Mechanism for Copper−Zinc Superoxide Dismutase,
PJ Hart, MM Balbirnie, NL Ogihara, AM Nersissian, MS Weiss, ...
Biochemistry 38 (7), 2167-2178, 1999
The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis
RW Strange, S Antonyuk, MA Hough, PA Doucette, JA Rodriguez, PJ Hart, ...
Journal of molecular biology 328 (4), 877-891, 2003
Variation in aggregation propensities among ALS-associated variants of SOD1: correlation to human disease
M Prudencio, PJ Hart, DR Borchelt, PM Andersen
Human molecular genetics 18 (17), 3217-3226, 2009
Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants
MA Hough, JG Grossmann, SV Antonyuk, RW Strange, PA Doucette, ...
Proceedings of the National Academy of Sciences 101 (16), 5976-5981, 2004
Structure of the Hsp110: Hsc70 nucleotide exchange machine
JP Schuermann, J Jiang, J Cuellar, O Llorca, L Wang, LE Gimenez, S Jin, ...
Molecular cell 31 (2), 232-243, 2008
Shall we dance? How a multicopper oxidase chooses its electron transfer partner
L Quintanar, C Stoj, AB Taylor, PJ Hart, DJ Kosman, EI Solomon
Accounts of chemical research 40 (6), 445-452, 2007
The crystal structure of a 3D domain-swapped dimer of RNase A at a 2.1- resolution
Y Liu, PJ Hart, MP Schlunegger, D Eisenberg
Proceedings of the National Academy of Sciences 95 (7), 3437-3442, 1998
Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALS
CM Karch, M Prudencio, DD Winkler, PJ Hart, DR Borchelt
Proceedings of the National Academy of Sciences 106 (19), 7774-7779, 2009
The copper-iron connection in biology: structure of the metallo-oxidase Fet3p
AB Taylor, CS Stoj, L Ziegler, DJ Kosman, PJ Hart
Proceedings of the National Academy of Sciences 102 (43), 15459-15464, 2005
A missing link in cupredoxins: Crystal structure of cucumber stellacyanin at 1.6 resolution
PJ Hart, D Eisenberg, AM Nersissian, JS Valentine, RG Herrmann, ...
Protein science 5 (11), 2175-2183, 1996
Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant: Insights into the molecular basis for dimer stability
PA Doucette, LJ Whitson, X Cao, V Schirf, B Demeler, JS Valentine, ...
Journal of Biological Chemistry 279 (52), 54558-54566, 2004
The refined crystal structure of an endochitinase from Hordeum vulgare L. seeds at 1.8 resolution
PJ Hart, HD Pfluger, AF Monzingo, T Hollis, JD Robertus
J. Mol. Biol 248, 402-413, 1995
Uclacyanins, stellacyanins, and plantacyanins are distinct subfamilies of phytocyanins: Plant‐specific mononuclear blue copper proteins
AM Nersissian, JS Valentine, C Immoos, MG Hill, PJ Hart, G Williams, ...
Protein Science 7 (9), 1915-1929, 1998
Chitinases, chitosanases, and lysozymes can be divided into procaryotic and eucaryotic families sharing a conserved core
AF Monzingo, EM Marcotte, PJ Hart, JD Robertas
nature structural biology 3 (2), 133-140, 1996
Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites
CLL Valentim, D Cioli, FD Chevalier, X Cao, AB Taylor, SP Holloway, ...
Science 342 (6164), 1385-1389, 2013
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