Tetrazole photoclick chemistry: reinvestigating its suitability as a bioorthogonal reaction and potential applications Z Li, L Qian, L Li, JC Bernhammer, HV Huynh, JS Lee, SQ Yao Angewandte Chemie International Edition 55 (6), 2002-2006, 2016 | 204 | 2016 |
Two-photon small molecule enzymatic probes L Qian, L Li, SQ Yao Accounts of Chemical Research 49 (4), 626-634, 2016 | 132 | 2016 |
Cell‐penetrating poly (disulfide) assisted intracellular delivery of mesoporous silica nanoparticles for inhibition of miR‐21 function and detection of subsequent therapeutic … C Yu, L Qian, J Ge, J Fu, P Yuan, SCL Yao, SQ Yao Angewandte Chemie International Edition 55 (32), 9272-9276, 2016 | 121 | 2016 |
Intracellular delivery of functional native antibodies under hypoxic conditions by using a biodegradable silica nanoquencher P Yuan, H Zhang, L Qian, X Mao, S Du, C Yu, B Peng, SQ Yao Angewandte Chemie International Edition 56 (41), 12481-12485, 2017 | 114 | 2017 |
Intracellular delivery of native proteins facilitated by cell‐penetrating poly (disulfide) s L Qian, J Fu, P Yuan, S Du, W Huang, L Li, SQ Yao Angewandte Chemie 130 (6), 1548-1552, 2018 | 113 | 2018 |
A Small‐Molecule Probe for Selective Profiling and Imaging of Monoamine Oxidase B Activities in Models of Parkinson’s Disease L Li, CW Zhang, J Ge, L Qian, BH Chai, Q Zhu, JS Lee, KL Lim, SQ Yao Angewandte Chemie International Edition 54 (37), 10821-10825, 2015 | 100 | 2015 |
Single‐vehicular delivery of antagomir and small molecules to inhibit miR‐122 function in hepatocellular carcinoma cells by using “smart” mesoporous silica nanoparticles C Yu, L Qian, M Uttamchandani, L Li, SQ Yao Angewandte Chemie International Edition 54 (36), 10574-10578, 2015 | 70 | 2015 |
Red-emitting DPSB-based conjugated polymer nanoparticles with high two-photon brightness for cell membrane imaging P Liu, S Li, Y Jin, L Qian, N Gao, SQ Yao, F Huang, QH Xu, Y Cao ACS applied materials & interfaces 7 (12), 6754-6763, 2015 | 51 | 2015 |
Recent advances in construction of small molecule-based fluorophore-drug conjugates W Lang, C Yuan, L Zhu, S Du, L Qian, J Ge, SQ Yao Journal of Pharmaceutical Analysis 10 (5), 434-443, 2020 | 29 | 2020 |
The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics L Qian, X Lin, X Gao, RU Khan, JY Liao, S Du, J Ge, S Zeng, SQ Yao Chemical reviews 123 (12), 7782-7853, 2023 | 24 | 2023 |
Catalytic Atroposelective Dynamic Kinetic Resolution of Biaryl Lactones with Activated Isocyanides L Qian, LF Tao, WT Wang, E Jameel, ZH Luo, T Zhang, Y Zhao, JY Liao Organic Letters 23 (13), 5086-5091, 2021 | 21 | 2021 |
Visualization of monoamine oxidases in living cells using “Turn-ON” fluorescence resonance energy transfer probes X Li, J Yu, Q Zhu, L Qian, L Li, Y Zheng, SQ Yao Analyst 139 (23), 6092-6095, 2014 | 21 | 2014 |
Recent progress in the molecular imaging of therapeutic monoclonal antibodies K He, S Zeng, L Qian Journal of Pharmaceutical Analysis 10 (5), 397-413, 2020 | 20 | 2020 |
Live-cell imaging and profiling of c-Jun N-terminal kinases using covalent inhibitor-derived probes L Qian, S Pan, JS Lee, J Ge, L Li, SQ Yao Chemical communications 55 (8), 1092-1095, 2019 | 19 | 2019 |
Diastereo‐and Enantioselective Silver‐Catalyzed [3+ 3] Cycloaddition and Kinetic Resolution of Azomethine Imines with Activated Isocyanides LF Tao, S Zhang, F Huang, WT Wang, ZH Luo, L Qian, JY Liao Angewandte Chemie International Edition 61 (23), e202202679, 2022 | 18 | 2022 |
Torsional Strain‐Independent Catalytic Enantioselective Synthesis of Biaryl Atropisomers ZH Luo, WT Wang, TY Tang, S Zhang, F Huang, D Hu, LF Tao, L Qian, ... Angewandte Chemie International Edition 61 (43), e202211303, 2022 | 15 | 2022 |
Structure‐Based Specific Detection and Inhibition of Monoamine Oxidases and Their Applications in Central Nervous System Diseases R Shi, Q Wu, C Xin, H Yu, KL Lim, X Li, Z Shi, CW Zhang, L Qian, L Li, ... Chembiochem 20 (12), 1487-1497, 2019 | 15 | 2019 |
Fused Bicyclic Caspase‐1 Inhibitors Assembled by Copper‐Free Strain‐Promoted Alkyne–Azide Cycloaddition (SPAAC) L Qian, CJ Zhang, J Wu, SQ Yao Chemistry–A European Journal 23 (2), 360-369, 2017 | 12 | 2017 |
Prediction of maximum absorption wavelength using deep neural networks J Shao, Y Liu, J Yan, ZY Yan, Y Wu, Z Ru, JY Liao, X Miao, L Qian Journal of Chemical Information and Modeling 62 (6), 1368-1375, 2022 | 11 | 2022 |
Two-photon enzymatic probes visualizing sub-cellular/deep-brain caspase activities in neurodegenerative models L Qian, CW Zhang, Y Mao, L Li, N Gao, KL Lim, QH Xu, SQ Yao Scientific reports 6 (1), 26385, 2016 | 11 | 2016 |