Highly enantioselective iridium-catalyzed hydrogenation of heteroaromatic compounds, quinolines WB Wang, SM Lu, PY Yang, XW Han, YG Zhou Journal of the American Chemical Society 125 (35), 10536-10537, 2003 | 573 | 2003 |
Activity-based proteome profiling of potential cellular targets of orlistat− an FDA-approved drug with anti-tumor activities PY Yang, K Liu, MH Ngai, MJ Lear, MR Wenk, SQ Yao Journal of the American Chemical Society 132 (2), 656-666, 2010 | 256 | 2010 |
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis F Wang, D Sambandan, R Halder, J Wang, SM Batt, B Weinrick, I Ahmad, ... Proceedings of the National Academy of Sciences 110 (27), E2510-E2517, 2013 | 250 | 2013 |
Multicolor, one-and two-photon imaging of enzymatic activities in live cells with fluorescently Quenched Activity-Based Probes (qABPs) M Hu, L Li, H Wu, Y Su, PY Yang, M Uttamchandani, QH Xu, SQ Yao Journal of the American Chemical Society 133 (31), 12009-12020, 2011 | 146 | 2011 |
A small molecule promotes mitochondrial fusion in mammalian cells D Wang, J Wang, GMC Bonamy, S Meeusen, RG Brusch, C Turk, P Yang, ... Angewandte Chemie International Edition 51 (37), 9302-9305, 2012 | 138 | 2012 |
The enantioselective total synthesis of alkaloid (−)-galipeine PY Yang, YG Zhou Tetrahedron: Asymmetry 15 (7), 1145-1149, 2004 | 130 | 2004 |
Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria X Luo, G Fu, RE Wang, X Zhu, C Zambaldo, R Liu, T Liu, X Lyu, J Du, ... Nature chemical biology 13 (8), 845-849, 2017 | 126 | 2017 |
Design of switchable chimeric antigen receptor T cells targeting breast cancer Y Cao, DT Rodgers, J Du, I Ahmad, EN Hampton, JSY Ma, M Mazagova, ... Angewandte Chemie International Edition 55 (26), 7520-7524, 2016 | 121 | 2016 |
High-throughput synthesis of azide libraries suitable for direct “click” chemistry and in situ screening R Srinivasan, LP Tan, H Wu, PY Yang, KA Kalesh, SQ Yao Organic & Biomolecular Chemistry 7 (9), 1821-1828, 2009 | 96 | 2009 |
Genetic incorporation of histidine derivatives using an engineered pyrrolysyl-tRNA synthetase H Xiao, FB Peters, PY Yang, S Reed, JR Chittuluru, PG Schultz ACS chemical biology 9 (5), 1092-1096, 2014 | 95 | 2014 |
Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication N Nasheri, M Joyce, Y Rouleau, P Yang, S Yao, DL Tyrrell, JP Pezacki Chemistry & biology 20 (4), 570-582, 2013 | 94 | 2013 |
Activity-Based Protein Profiling: Recent Advances in Probe Development and Applications P Yang, K Liu ChemBioChem 16 (5), 712-724, 2015 | 90 | 2015 |
Synthesis and Highly Enantioselective Hydrogenation of Exocyclic Enamides: (Z)-3-Arylidene-4-acetyl-3,4-dihydro-2H- 1,4-benzoxazines YG Zhou, PY Yang, XW Han The Journal of Organic Chemistry 70 (5), 1679-1683, 2005 | 88 | 2005 |
High-Throughput Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (MptpB) Inhibitors Using Click Chemistry LP Tan, H Wu, PY Yang, KA Kalesh, X Zhang, M Hu, R Srinivasan, ... Organic Letters 11 (22), 5102-5105, 2009 | 84 | 2009 |
Design, Synthesis and Biological Evaluation of Potent Azadipeptide Nitrile Inhibitors and Activity‐Based Probes as Promising Anti‐Trypanosoma brucei Agents PY Yang, M Wang, L Li, H Wu, CY He, SQ Yao Chemistry–A European Journal 18 (21), 6528-6541, 2012 | 72 | 2012 |
A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli A Chatterjee, H Xiao, PY Yang, G Soundararajan, PG Schultz Angew Chem Int Ed Engl 52 (19), 5106-9, 2013 | 70 | 2013 |
Recombinant thiopeptides containing noncanonical amino acids X Luo, C Zambaldo, T Liu, Y Zhang, W Xuan, C Wang, SA Reed, PY Yang, ... Proceedings of the National Academy of Sciences 113 (13), 3615-3620, 2016 | 68 | 2016 |
Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei PY Yang, M Wang, CY He, SQ Yao Chemical communications 48 (6), 835-837, 2012 | 68 | 2012 |
Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery PY Yang, H Zou, E Chao, L Sherwood, V Nunez, M Keeney, ... Proceedings of the National Academy of Sciences 113 (15), 4140-4145, 2016 | 59 | 2016 |
A peptide aldehyde microarray for high-throughput profiling of cellular events H Wu, J Ge, PY Yang, J Wang, M Uttamchandani, SQ Yao Journal of the American Chemical Society 133 (6), 1946-1954, 2011 | 56 | 2011 |