Mahesh Uttamchandani
Mahesh Uttamchandani
Assistant Professor, Departments of Chemistry and Biological Sciences, NUS
Verified email at - Homepage
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Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism
K Thangavelu, CQ Pan, T Karlberg, G Balaji, M Uttamchandani, V Suresh, ...
Proceedings of the National Academy of Sciences 109 (20), 7705-7710, 2012
Developing site-specific immobilization strategies of peptides in a microarray
ML Lesaicherre, M Uttamchandani, GYJ Chen, SQ Yao
Bioorganic & Medicinal Chemistry Letters 12 (16), 2079-2083, 2002
Small molecule microarrays: recent advances and applications
M Uttamchandani, DP Walsh, SQ Yao, YT Chang
Current opinion in chemical biology 9 (1), 4-13, 2005
Enzymatic profiling system in a small-molecule microarray
Q Zhu, M Uttamchandani, D Li, ML Lesaicherre, SQ Yao
Organic Letters 5 (8), 1257-1260, 2003
Antibody-based fluorescence detection of kinase activity on a peptide array
ML Lesaicherre, M Uttamchandani, GYJ Chen, SQ Yao
Bioorganic & Medicinal Chemistry Letters 12 (16), 2085-2088, 2002
Protein and small molecule microarrays: powerful tools for high-throughput proteomics
M Uttamchandani, J Wang, SQ Yao
Molecular Biosystems 2 (1), 58-68, 2006
Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases
R Srinivasan, M Uttamchandani, SQ Yao
Organic letters 8 (4), 713-716, 2006
Multicolor, one-and two-photon imaging of enzymatic activities in live cells with fluorescently Quenched Activity-Based Probes (qABPs)
M Hu, L Li, H Wu, Y Su, PY Yang, M Uttamchandani, QH Xu, SQ Yao
Journal of the American Chemical Society 133 (31), 12009-12020, 2011
Solid-phase synthesis of peptide vinyl sulfones as potential inhibitors and activity-based probes of cysteine proteases
G Wang, U Mahesh, GYJ Chen, SQ Yao
Organic letters 5 (5), 737-740, 2003
Applications of microarrays in pathogen detection and biodefence
M Uttamchandani, JL Neo, BNZ Ong, S Moochhala
Trends in biotechnology 27 (1), 53-61, 2009
Developing a Strategy for Activity‐Based Detection of Enzymes in a Protein Microarray
GYJ Chen, M Uttamchandani, Q Zhu, G Wang, SQ Yao
ChemBioChem 4 (4), 336-339, 2003
Peptide microarrays: next generation biochips for detection, diagnostics and high-throughput screening
M Uttamchandani, SQ Yao
Current pharmaceutical design 14 (24), 2428-2438, 2008
Combinatorial peptide microarrays for the rapid determination of kinase specificity
M Uttamchandani, EWS Chan, GYJ Chen, SQ Yao
Bioorganic & medicinal chemistry letters 13 (18), 2997-3000, 2003
Activity‐based protein profiling: new developments and directions in functional proteomics
M Uttamchandani, J Li, H Sun, SQ Yao
ChemBioChem 9 (5), 667-675, 2008
Microarrays of tagged combinatorial triazine libraries in the discovery of small-molecule ligands of human IgG
M Uttamchandani, DP Walsh, SM Khersonsky, X Huang, SQ Yao, ...
Journal of combinatorial chemistry 6 (6), 862-868, 2004
Array-based technologies and their applications in proteomics.
GY Chen, M Uttamchandani, RY Lue, ML Lesaicherrea, SQ Yao
Current advances in peptide and small molecule microarray technologies
YM Foong, J Fu, SQ Yao, M Uttamchandani
Current opinion in chemical biology 16 (1-2), 234-242, 2012
Next generation chemical proteomic tools for rapid enzyme profiling
M Uttamchandani, CHS Lu, SQ Yao
Accounts of chemical research 42 (8), 1183-1192, 2009
Peptide microarray for high‐throughput determination of phosphatase specificity and biology
H Sun, CHS Lu, M Uttamchandani, Y Xia, YC Liou, SQ Yao
Angewandte Chemie 120 (9), 1722-1726, 2008
Rapid assembly of matrix metalloprotease inhibitors using click chemistry
J Wang, M Uttamchandani, J Li, M Hu, SQ Yao
Organic letters 8 (17), 3821-3824, 2006
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