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Megan Holly Wright
Megan Holly Wright
University Academic Fellow
Verified email at leeds.ac.uk - Homepage
Title
Cited by
Cited by
Year
Chemical proteomics approaches for identifying the cellular targets of natural products
MH Wright, SA Sieber
Natural product reports 33 (5), 681-708, 2016
3762016
Protein myristoylation in health and disease
MH Wright, WP Heal, DJ Mann, EW Tate
Journal of chemical biology 3, 19-35, 2010
2882010
Global profiling of co- and post-translationally N-myristoylated proteomes in human cells
E Thinon, RA Serwa, M Broncel, JA Brannigan, U Brassat, MH Wright, ...
Nature communications 5, 4919, 2014
2442014
Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach
MH Wright, B Clough, MD Rackham, K Rangachari, JA Brannigan, ...
Nature chemistry 6 (2), 112-121, 2014
2162014
Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation
DS Guttery, B Poulin, A Ramaprasad, RJ Wall, DJP Ferguson, D Brady, ...
Cell host & microbe 16 (1), 128-140, 2014
1252014
Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry
WP Heal, MH Wright, E Thinon, EW Tate
Nature protocols 7 (1), 105-117, 2012
1142012
Bioorthogonal chemical tagging of protein cholesterylation in living cells
WP Heal, B Jovanovic, S Bessin, MH Wright, AI Magee, EW Tate
Chemical Communications 47 (14), 4081-4083, 2011
992011
Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics
B Morkunas, WRJD Galloway, M Wright, BM Ibbeson, JT Hodgkinson, ...
Organic & biomolecular chemistry 10 (42), 8452-8464, 2012
922012
Global analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani
MH Wright, D Paape, EM Storck, RA Serwa, DF Smith, EW Tate
Chemistry & biology 22 (3), 342-354, 2015
892015
Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa
JT Hodgkinson, WRJD Galloway, M Wright, IK Mati, RL Nicholson, ...
Organic & biomolecular chemistry 10 (30), 6032-6044, 2012
802012
N-Myristoyltransferase as a potential drug target in malaria and leishmaniasis
EW Tate, AS Bell, MD Rackham, MH Wright
Parasitology 141 (1), 37-49, 2014
782014
Structure-based design of potent and selective Leishmania N-myristoyltransferase inhibitors
JA Hutton, V Goncalves, JA Brannigan, D Paape, MH Wright, TM Waugh, ...
Journal of medicinal chemistry 57 (20), 8664-8670, 2014
712014
Making a Long Journey Short: Alkyne Functionalization of Natural Product Scaffolds
J Lehmann, MH Wright, SA Sieber
Chemistry-A European Journal 22 (14), 4666-4678, 2016
672016
Redox regulation of cell proliferation: Bioinformatics and redox proteomics approaches to identify redox-sensitive cell cycle regulators
CH Foyer, MH Wilson, MH Wright
Free Radical Biology and Medicine 122, 137-149, 2018
652018
Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite
B Poulin, EM Patzewitz, D Brady, O Silvie, MH Wright, DJP Ferguson, ...
Biology open 2 (11), 1160-1170, 2013
642013
Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei
MH Wright, D Paape, HP Price, DF Smith, EW Tate
ACS infectious diseases 2 (6), 427-441, 2016
552016
On the move: redox-dependent protein relocation in plants
CH Foyer, A Baker, M Wright, IA Sparkes, A Mhamdi, JHM Schippers, ...
Journal of experimental botany 71 (2), 620-631, 2020
492020
Chemical probes unravel an antimicrobial defense response triggered by binding of the human opioid dynorphin to a bacterial sensor kinase
MH Wright, C Fetzer, SA Sieber
Journal of the American Chemical Society 139 (17), 6152-6159, 2017
482017
Catalase: A critical node in the regulation of cell fate
A Baker, CC Lin, C Lett, B Karpinska, MH Wright, CH Foyer
Free Radical Biology and Medicine 199, 56-66, 2023
382023
New developments in probing and targeting protein acylation in malaria, leishmaniasis and African sleeping sickness
M Ritzefeld, MH Wright, EW Tate
Parasitology 145 (2), 157-174, 2018
352018
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