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Aaron Haeusler
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The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ...
Nature 525 (7567), 56-61, 2015
10892015
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
AR Haeusler, CJ Donnelly, G Periz, EAJ Simko, PG Shaw, MS Kim, ...
Nature 507 (7491), 195-200, 2014
10592014
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention
CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ...
Neuron 80 (2), 415-428, 2013
10592013
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease
AR Haeusler, CJ Donnelly, JD Rothstein
Nature Reviews Neuroscience 17 (6), 383-395, 2016
2442016
Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress
T Westergard, K McAvoy, K Russell, X Wen, Y Pang, B Morris, P Pasinelli, ...
EMBO molecular medicine 11 (2), e9423, 2019
1182019
G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA
EAJ Simko, H Liu, T Zhang, A Velasquez, S Teli, AR Haeusler, J Wang
Nucleic acids research 48 (13), 7421-7438, 2020
712020
Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ALS/FTD is rescued by SV 2 replenishment
BK Jensen, MH Schuldi, K McAvoy, KA Russell, A Boehringer, BM Curran, ...
EMBO molecular medicine 12 (5), e10722, 2020
492020
FRET studies of a landscape of Lac repressor-mediated DNA loops
AR Haeusler, KA Goodson, TD Lillian, X Wang, S Goyal, NC Perkins, ...
Nucleic acids research 40 (10), 4432-4445, 2012
442012
Emerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration
J Wang, AR Haeusler, EAJ Simko
Cell Cycle 14 (4), 526-532, 2015
392015
A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes
BM Verdone, ME Cicardi, X Wen, S Sriramoji, K Russell, SS Markandaiah, ...
Scientific reports 12 (1), 5644, 2022
222022
LacI-DNA-IPTG loops: equilibria among conformations by single-molecule FRET
KA Goodson, Z Wang, AR Haeusler, JD Kahn, DS English
The Journal of Physical Chemistry B 117 (16), 4713-4722, 2013
172013
Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis‐linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice
BK Jensen, KJ McAvoy, NM Heinsinger, AC Lepore, H Ilieva, ...
Glia 70 (7), 1426-1449, 2022
152022
Breakdown of the central synapses in C9orf72-linked ALS/FTD
LT Ghaffari, D Trotti, AR Haeusler, BK Jensen
Frontiers in Molecular Neuroscience 15, 1005112, 2022
122022
The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion
KA Ozcan, LT Ghaffari, AR Haeusler
Scientific Reports 11 (1), 23213, 2021
82021
Differential response of C9orf72 transcripts following neuronal depolarization
LT Ghaffari, D Trotti, AR Haeusler
Iscience 26 (6), 2023
2023
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