The C9orf72 repeat expansion disrupts nucleocytoplasmic transport K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ... Nature 525 (7567), 56-61, 2015 | 1089 | 2015 |
C9orf72 nucleotide repeat structures initiate molecular cascades of disease AR Haeusler, CJ Donnelly, G Periz, EAJ Simko, PG Shaw, MS Kim, ... Nature 507 (7491), 195-200, 2014 | 1059 | 2014 |
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ... Neuron 80 (2), 415-428, 2013 | 1059 | 2013 |
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease AR Haeusler, CJ Donnelly, JD Rothstein Nature Reviews Neuroscience 17 (6), 383-395, 2016 | 244 | 2016 |
Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress T Westergard, K McAvoy, K Russell, X Wen, Y Pang, B Morris, P Pasinelli, ... EMBO molecular medicine 11 (2), e9423, 2019 | 118 | 2019 |
G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA EAJ Simko, H Liu, T Zhang, A Velasquez, S Teli, AR Haeusler, J Wang Nucleic acids research 48 (13), 7421-7438, 2020 | 71 | 2020 |
Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ALS/FTD is rescued by SV 2 replenishment BK Jensen, MH Schuldi, K McAvoy, KA Russell, A Boehringer, BM Curran, ... EMBO molecular medicine 12 (5), e10722, 2020 | 49 | 2020 |
FRET studies of a landscape of Lac repressor-mediated DNA loops AR Haeusler, KA Goodson, TD Lillian, X Wang, S Goyal, NC Perkins, ... Nucleic acids research 40 (10), 4432-4445, 2012 | 44 | 2012 |
Emerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration J Wang, AR Haeusler, EAJ Simko Cell Cycle 14 (4), 526-532, 2015 | 39 | 2015 |
A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes BM Verdone, ME Cicardi, X Wen, S Sriramoji, K Russell, SS Markandaiah, ... Scientific reports 12 (1), 5644, 2022 | 22 | 2022 |
LacI-DNA-IPTG loops: equilibria among conformations by single-molecule FRET KA Goodson, Z Wang, AR Haeusler, JD Kahn, DS English The Journal of Physical Chemistry B 117 (16), 4713-4722, 2013 | 17 | 2013 |
Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis‐linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice BK Jensen, KJ McAvoy, NM Heinsinger, AC Lepore, H Ilieva, ... Glia 70 (7), 1426-1449, 2022 | 15 | 2022 |
Breakdown of the central synapses in C9orf72-linked ALS/FTD LT Ghaffari, D Trotti, AR Haeusler, BK Jensen Frontiers in Molecular Neuroscience 15, 1005112, 2022 | 12 | 2022 |
The effects of molecular crowding and CpG hypermethylation on DNA G-quadruplexes formed by the C9orf72 nucleotide repeat expansion KA Ozcan, LT Ghaffari, AR Haeusler Scientific Reports 11 (1), 23213, 2021 | 8 | 2021 |
Differential response of C9orf72 transcripts following neuronal depolarization LT Ghaffari, D Trotti, AR Haeusler Iscience 26 (6), 2023 | | 2023 |