Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents D Ryu, L Mouchiroud, PA Andreux, E Katsyuba, N Moullan, ... Nature medicine 22 (8), 879-888, 2016 | 875 | 2016 |
Tetracyclines disturb mitochondrial function across eukaryotic models: a call for caution in biomedical research N Moullan, L Mouchiroud, X Wang, D Ryu, EG Williams, A Mottis, ... Cell reports 10 (10), 1681-1691, 2015 | 537 | 2015 |
Two conserved histone demethylases regulate mitochondrial stress-induced longevity C Merkwirth, V Jovaisaite, J Durieux, O Matilainen, SD Jordan, PM Quiros, ... Cell 165 (5), 1209-1223, 2016 | 352 | 2016 |
Multi-omic measurements of heterogeneity in HeLa cells across laboratories Y Liu, Y Mi, T Mueller, S Kreibich, EG Williams, A Van Drogen, C Borel, ... Nature biotechnology 37 (3), 314-322, 2019 | 348 | 2019 |
Systems proteomics of liver mitochondria function EG Williams, Y Wu, P Jha, S Dubuis, P Blattmann, CA Argmann, ... Science 352 (6291), aad0189, 2016 | 321 | 2016 |
NCoR1 is a conserved physiological modulator of muscle mass and oxidative function H Yamamoto, EG Williams, L Mouchiroud, C Cantó, W Fan, M Downes, ... Cell 147 (4), 827-839, 2011 | 302 | 2011 |
Pharmacological Inhibition of poly (ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle E Pirinen, C Canto, YS Jo, L Morato, H Zhang, KJ Menzies, EG Williams, ... Cell metabolism 19 (6), 1034-1041, 2014 | 295 | 2014 |
Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits AM McKnite, ME Perez-Munoz, L Lu, EG Williams, S Brewer, PA Andreux, ... PloS one 7 (6), e39191, 2012 | 253 | 2012 |
Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population Y Wu, EG Williams, S Dubuis, A Mottis, V Jovaisaite, SM Houten, ... Cell 158 (6), 1415-1430, 2014 | 252 | 2014 |
Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits PA Andreux, EG Williams, H Koutnikova, RH Houtkooper, MF Champy, ... Cell 150 (6), 1287-1299, 2012 | 234 | 2012 |
A platform for experimental precision medicine: The extended BXD mouse family DG Ashbrook, D Arends, P Prins, MK Mulligan, S Roy, EG Williams, ... Cell systems 12 (3), 235-247. e9, 2021 | 162* | 2021 |
Joint mouse–human phenome-wide association to test gene function and disease risk X Wang, AK Pandey, MK Mulligan, EG Williams, K Mozhui, Z Li, ... Nature communications 7 (1), 10464, 2016 | 157 | 2016 |
Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells Y Liu, C Borel, L Li, T Müller, EG Williams, PL Germain, M Buljan, T Sajic, ... Nature communications 8 (1), 1212, 2017 | 137 | 2017 |
Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers SC Hasenfuss, L Bakiri, MK Thomsen, EG Williams, J Auwerx, EF Wagner Cell Metabolism 19 (1), 84-95, 2014 | 130 | 2014 |
Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans T Van De Weijer, E Phielix, L Bilet, EG Williams, ER Ropelle, A Bierwagen, ... Diabetes 64 (4), 1193-1201, 2015 | 127 | 2015 |
Diagnostics and correction of batch effects in large‐scale proteomic studies: a tutorial J Čuklina, CH Lee, EG Williams, T Sajic, BC Collins, ... Molecular systems biology 17 (8), e10240, 2021 | 109 | 2021 |
A conserved mito-cytosolic translational balance links two longevity pathways M Molenaars, GE Janssens, EG Williams, A Jongejan, J Lan, S Rabot, ... Cell metabolism 31 (3), 549-563. e7, 2020 | 109 | 2020 |
The convergence of systems and reductionist approaches in complex trait analysis EG Williams, J Auwerx Cell 162 (1), 23-32, 2015 | 74 | 2015 |
Systems analyses reveal physiological roles and genetic regulators of liver lipid species P Jha, MT McDevitt, R Gupta, PM Quiros, EG Williams, K Gariani, ... Cell Systems 6 (6), 722-733. e6, 2018 | 63 | 2018 |
An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement EG Williams, L Mouchiroud, M Frochaux, A Pandey, PA Andreux, ... PLoS genetics 10 (9), e1004673, 2014 | 63 | 2014 |