AMPK phosphorylation of raptor mediates a metabolic checkpoint DM Gwinn, DB Shackelford, DF Egan, MM Mihaylova, A Mery, ... Molecular cell 30 (2), 214-226, 2008 | 4481 | 2008 |
Small molecule inhibition of the autophagy kinase ULK1 and identification of ULK1 substrates DF Egan, MGH Chun, M Vamos, H Zou, J Rong, CJ Miller, HJ Lou, ... Molecular cell 59 (2), 285-297, 2015 | 712 | 2015 |
Determination of protease cleavage site motifs using mixture-based oriented peptide libraries BE Turk, LL Huang, ET Piro, LC Cantley Nature biotechnology 19 (7), 661-667, 2001 | 696 | 2001 |
Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin EC Griffith, Z Su, BE Turk, S Chen, YH Chang, Z Wu, K Biemann, JO Liu Chemistry & biology 4 (6), 461-471, 1997 | 556 | 1997 |
Linear motif atlas for phosphorylation-dependent signaling ML Miller, LJ Jensen, F Diella, C Jørgensen, M Tinti, L Li, M Hsiung, ... Science signaling 1 (35), ra2-ra2, 2008 | 534 | 2008 |
mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin SA Kang, ME Pacold, CL Cervantes, D Lim, HJ Lou, K Ottina, NS Gray, ... Science 341 (6144), 1236566, 2013 | 501 | 2013 |
Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs J Mok, PM Kim, HYK Lam, S Piccirillo, X Zhou, GR Jeschke, DL Sheridan, ... Science signaling 3 (109), ra12-ra12, 2010 | 416 | 2010 |
A rapid method for determining protein kinase phosphorylation specificity JE Hutti, ET Jarrell, JD Chang, DW Abbott, P Storz, A Toker, LC Cantley, ... Nature methods 1 (1), 27-29, 2004 | 409 | 2004 |
Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence SJ Fentress, MS Behnke, IR Dunay, M Mashayekhi, LM Rommereim, ... Cell host & microbe 8 (6), 484-495, 2010 | 368 | 2010 |
Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase D Papinski, M Schuschnig, W Reiter, L Wilhelm, CA Barnes, A Maiolica, ... Molecular cell 53 (3), 471-483, 2014 | 364 | 2014 |
An atlas of substrate specificities for the human serine/threonine kinome JL Johnson, TM Yaron, EM Huntsman, A Kerelsky, J Song, A Regev, ... Nature 613 (7945), 759-766, 2023 | 306 | 2023 |
The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice RD Etheridge, A Alaganan, K Tang, HJ Lou, BE Turk, LD Sibley Cell host & microbe 15 (5), 537-550, 2014 | 261 | 2014 |
Structure and substrate specificity of the Pim-1 kinase AN Bullock, J Debreczeni, AL Amos, S Knapp, BE Turk Journal of Biological Chemistry 280 (50), 41675-41682, 2005 | 240 | 2005 |
The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor BE Turk, TY Wong, R Schwarzenbacher, ET Jarrell, SH Leppla, RJ Collier, ... Nature structural & molecular biology 11 (1), 60-66, 2004 | 239 | 2004 |
Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation P Filippakopoulos, M Kofler, O Hantschel, GD Gish, F Grebien, E Salah, ... Cell 134 (5), 793-803, 2008 | 238 | 2008 |
Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10 CI Caescu, GR Jeschke, BE Turk Biochemical Journal 424 (1), 79-88, 2009 | 233 | 2009 |
The Arabidopsis ABA-activated kinase OST1 phosphorylates the bZIP transcription factor ABF3 and creates a 14-3-3 binding site involved in its turnover C Sirichandra, M Davanture, BE Turk, M Zivy, B Valot, J Leung, S Merlot PloS one 5 (11), e13935, 2010 | 232 | 2010 |
IκB kinase β phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-κB pathway JE Hutti, BE Turk, JM Asara, A Ma, LC Cantley, DW Abbott Molecular and cellular biology 27 (21), 7451-7461, 2007 | 213 | 2007 |
A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms AL Williamson, P Lecchi, BE Turk, Y Choe, PJ Hotez, JH McKerrow, ... Journal of Biological Chemistry 279 (34), 35950-35957, 2004 | 207 | 2004 |
Manipulation of host signalling pathways by anthrax toxins BE Turk Biochemical Journal 402 (3), 405-417, 2007 | 194 | 2007 |