Cytotoxic 3, 6-bis ((imidazolidinone) imino) acridines: synthesis, DNA binding and molecular modeling L Janovec, M Kožurková, D Sabolová, J Ungvarský, H Paulíková, ... Bioorganic & medicinal chemistry 19 (5), 1790-1801, 2011 | 106 | 2011 |
Neuroactive multifunctional tacrine congeners with cholinesterase, anti-amyloid aggregation and neuroprotective properties M Kozurkova, S Hamulakova, Z Gazova, H Paulikova, P Kristian Pharmaceuticals 4 (2), 382-418, 2011 | 90 | 2011 |
Cytotoxic activity of proflavine diureas: synthesis, antitumor, evaluation and DNA binding properties of 1′, 1 ″-(acridin-3, 6-diyl)-3′, 3 ″-dialkyldiureas M Kožurková, D Sabolová, L Janovec, J Mikeš, J Ungvarský, ... Bioorganic & medicinal chemistry 16 (7), 3976-3984, 2008 | 65 | 2008 |
Interaction of a copper (II)–Schiff base complexes with calf thymus DNA and their antimicrobial activity D Sabolová, M Kožurková, T Plichta, Z Ondrušová, D Hudecová, ... International journal of biological macromolecules 48 (2), 319-325, 2011 | 58 | 2011 |
DNA binding properties and evaluation of cytotoxic activity of 9, 10-bis-N-substituted (aminomethyl) anthracenes M Kožurková, D Sabolová, H Paulíková, L Janovec, P Kristian, ... International journal of biological macromolecules 41 (4), 415-422, 2007 | 54 | 2007 |
Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers S Hamulakova, J Imrich, L Janovec, P Kristian, I Danihel, O Holas, ... International journal of biological macromolecules 70, 435-439, 2014 | 51 | 2014 |
3, 6-Bis (3-alkylguanidino) acridines as DNA-intercalating antitumor agents J Plsikova, L Janovec, J Koval, J Ungvarsky, J Mikes, R Jendzelovsky, ... European journal of medicinal chemistry 57, 283-295, 2012 | 51 | 2012 |
Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds J Janočková, J Plšíková, J Kašpárková, V Brabec, R Jendželovský, ... European Journal of Pharmaceutical Sciences 76, 192-202, 2015 | 49 | 2015 |
Synthesis, DNA interaction, and cytotoxic activity of a novel proflavine− dithiazolidinone pharmacophore L Janovec, D Sabolová, M Kožurková, H Paulíková, P Kristian, ... Bioconjugate chemistry 18 (1), 93-100, 2007 | 36 | 2007 |
Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors J Janočková, J Plšíková, R Jendželovský, J Mikeš, J Kašpárková, ... Bioorganic Chemistry 59, 168-176, 2015 | 35 | 2015 |
New spiro tria (thia) zolidine acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds OM Salem, M Vilková, J JanoĿková, R Jendželovský, P FedoroĿko, ... International journal of biological macromolecules 86, 690-700, 2016 | 34 | 2016 |
A review on acridinylthioureas and its derivatives: biological and cytotoxic activity M Kožurková, D Sabolová, P Kristian Journal of Applied Toxicology 37 (10), 1132-1139, 2017 | 28 | 2017 |
DNA/BSA binding ability and genotoxic effect of mono-and binuclear copper (II) complexes containing a Schiff base derived from salicylaldehyde and D, L-glutamic acid L Andrezálová, J Plšíková, J Janočková, K Koňariková, I Žitňanová, ... Journal of Organometallic Chemistry 827, 67-77, 2017 | 28 | 2017 |
Novel trisubstituted acridines as human telomeric quadruplex binding ligands J Ungvarsky, J Plsikova, L Janovec, J Koval, J Mikes, L Mikesová, ... Bioorganic Chemistry 57, 13-29, 2014 | 28 | 2014 |
Determination of the binding affinities of plasmid DNA using fluorescent intercalators possessing an acridine skeleton D Sabolova, M Kožurková, P Kristian, I Danihel, D Podhradský, J Imrich International journal of biological macromolecules 38 (2), 94-98, 2006 | 27 | 2006 |
DNA binding acridine–thiazolidinone agents affecting intracellular glutathione H Paulíková, Z Vantová, Ľ Hunáková, L Čižeková, M Čarná, M Kožurková, ... Bioorganic & medicinal chemistry 20 (24), 7139-7148, 2012 | 26 | 2012 |
A new look at 9‐substituted acridines with various biological activities M Kozurkova, D Sabolova, P Kristian Journal of Applied Toxicology 41 (1), 175-189, 2021 | 25 | 2021 |
Proflavine/acriflavine derivatives with versatile biological activities D Sabolova, P Kristian, M Kozurkova Journal of Applied Toxicology 40 (1), 64-71, 2020 | 25 | 2020 |
Cytotoxic activity of acridin-3, 6-diyl dithiourea hydrochlorides in human leukemia line HL-60 and resistant subline HL-60/ADR Z Vantová, H Paulíková, D Sabolová, M Kožurková, M Sucháňová, ... International journal of biological macromolecules 45 (2), 174-180, 2009 | 25 | 2009 |
Coumarin Derivatives in Pharmacotherapy of Alzheimer´ s Disease S Hamulakova, M Kozurkova, K Kuca Current Organic Chemistry 21 (7), 602-612, 2017 | 24 | 2017 |