| Binding interactions between long noncoding RNA HOTAIR and PRC2 proteins L Wu, P Murat, D Matak-Vinkovic, A Murrell, S Balasubramanian Biochemistry 52 (52), 9519-9527, 2013 | 200 | 2013 |
| Structural characterization of human heparanase reveals insights into substrate recognition L Wu, CM Viola, AM Brzozowski, GJ Davies Nature structural & molecular biology 22 (12), 1016-1022, 2015 | 167 | 2015 |
| Activity-based probes for functional interrogation of retaining β-glucuronidases L Wu, J Jiang, Y Jin, WW Kallemeijn, CL Kuo, M Artola, W Dai, C Van Elk, ... Nature chemical biology 13 (8), 867-873, 2017 | 115 | 2017 |
| An overview of activity-based probes for glycosidases L Wu, Z Armstrong, SP Schröder, C de Boer, M Artola, JMFG Aerts, ... Current opinion in chemical biology 53, 25-36, 2019 | 112 | 2019 |
| 1, 6-Cyclophellitol cyclosulfates: a new class of irreversible glycosidase inhibitor M Artola, L Wu, MJ Ferraz, CL Kuo, L Raich, IZ Breen, WA Offen, ... ACS central science 3 (7), 784-793, 2017 | 77 | 2017 |
| A fluorescence polarization activity-based protein profiling assay in the discovery of potent, selective inhibitors for human nonlysosomal glucosylceramidase D Lahav, B Liu, RJ van den Berg, AMCH van den Nieuwendijk, ... Journal of the American Chemical Society 139 (40), 14192-14197, 2017 | 73 | 2017 |
| Detection of active mammalian GH31 α-glucosidases in health and disease using in-class, broad-spectrum activity-based probes J Jiang, CL Kuo, L Wu, C Franke, WW Kallemeijn, BI Florea, E van Meel, ... ACS central science 2 (5), 351-358, 2016 | 73 | 2016 |
| Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes SP Schröder, C De Boer, NGS McGregor, RJ Rowland, O Moroz, ... ACS central science 5 (6), 1067-1078, 2019 | 55 | 2019 |
| Bacterial β-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2) R Charoenwattanasatien, S Pengthaisong, I Breen, R Mutoh, S Sansenya, ... ACS chemical biology 11 (7), 1891-1900, 2016 | 53 | 2016 |
| Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors Z Armstrong, CL Kuo, D Lahav, B Liu, R Johnson, TJM Beenakker, ... Journal of the American Chemical Society 142 (30), 13021-13029, 2020 | 42 | 2020 |
| Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo C de Boer, Z Armstrong, VAJ Lit, U Barash, G Ruijgrok, I Boyango, ... Proceedings of the National Academy of Sciences 119 (31), e2203167119, 2022 | 38 | 2022 |
| Cryo-plasma FIB/SEM volume imaging of biological specimens M Dumoux, T Glen, JLR Smith, EML Ho, LMA Perdigão, A Pennington, ... Elife 12, e83623, 2023 | 34 | 2023 |
| Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V JF Darby, AK Gilio, B Piniello, C Roth, E Blagova, RE Hubbard, C Rovira, ... ACS Catalysis 10 (15), 8590-8596, 2020 | 27 | 2020 |
| Gluco-1H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor SP Schröder, L Wu, M Artola, T Hansen, WA Offen, MJ Ferraz, KY Li, ... Journal of the American Chemical Society 140 (15), 5045-5048, 2018 | 27 | 2018 |
| 1,6-epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease K Kok, CL Kuo, RE Katzy, LT Lelieveld, L Wu, V Roig-Zamboni, ... Journal of the American Chemical Society 144 (32), 14819-14827, 2022 | 23 | 2022 |
| Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action P Bule, L Chuzel, E Blagova, L Wu, MA Gray, B Henrissat, E Rapp, ... Nature Communications 10 (1), 4816, 2019 | 21 | 2019 |
| α-D-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal α-galactosidase A in Fabry disease M Artola, C Hedberg, RJ Rowland, L Raich, K Kytidou, L Wu, A Schaaf, ... Chemical Science 10 (40), 9233-9243, 2019 | 20 | 2019 |
| Structural insights into pixatimod (PG545) inhibition of heparanase, a key enzyme in cancer and viral infections M Chhabra, JC Wilson, L Wu, GJ Davies, NS Gandhi, V Ferro Chemistry–A European Journal 28 (11), e202104222, 2022 | 17 | 2022 |
| Selective fluorogenic β-glucocerebrosidase substrates for convenient analysis of enzyme activity in cell and tissue homogenates MC Deen, C Proceviat, X Shan, L Wu, DL Shen, GJ Davies, DJ Vocadlo ACS Chemical Biology 15 (4), 824-829, 2020 | 15 | 2020 |
| Structural insights into heparanase activity using a fluorogenic heparan sulfate disaccharide L Wu, N Wimmer, GJ Davies, V Ferro Chemical Communications 56 (89), 13780-13783, 2020 | 12 | 2020 |
