| Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction CK Deniston, J Salogiannis, S Mathea, DM Snead, I Lahiri, ... Nature 588 (7837), 344-349, 2020 | 202 | 2020 |
| Melanin Is Not Required for Turgor Generation but Enhances Cell-Wall Rigidity in Appressoria of the Corn Pathogen Colletotrichum graminicola N Ludwig, M Löhrer, M Hempel, S Mathea, I Schliebner, M Menzel, ... Molecular Plant-Microbe Interactions 27 (4), 315-327, 2014 | 109 | 2014 |
| Isoform-specific inhibition of cyclophilins S Daum, M Schumann, S Mathea, T Aumüller, MA Balsley, SL Constant, ... Biochemistry 48 (26), 6268-6277, 2009 | 89 | 2009 |
| Sfp-type 4′-phosphopantetheinyl transferase is indispensable for fungal pathogenicity R Horbach, A Graf, F Weihmann, L Antelo, S Mathea, JC Liermann, ... The Plant Cell 21 (10), 3379-3396, 2009 | 83 | 2009 |
| Structural insights into pseudokinase domains of receptor tyrosine kinases JB Sheetz, S Mathea, H Karvonen, K Malhotra, D Chatterjee, W Niininen, ... Molecular cell 79 (3), 390-405. e7, 2020 | 78 | 2020 |
| Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level D Coutandin, C Osterburg, RK Srivastav, M Sumyk, S Kehrloesser, ... Elife 5, e13909, 2016 | 67 | 2016 |
| Modulating androgen receptor-driven transcription in prostate cancer with selective CDK9 inhibitors A Richters, SK Doyle, DB Freeman, C Lee, BS Leifer, S Jagannathan, ... Cell chemical biology 28 (2), 134-147. e14, 2021 | 64 | 2021 |
| Comprehensive landscape of active deubiquitinating enzymes profiled by advanced chemoproteomics A Pinto-Fernández, S Davis, AB Schofield, HC Scott, P Zhang, E Salah, ... Frontiers in chemistry 7, 592, 2019 | 56 | 2019 |
| Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2 SH Schmidt, JH Weng, PC Aoto, D Boassa, S Mathea, S Silletti, J Hu, ... Proceedings of the National Academy of Sciences 118 (23), e2100844118, 2021 | 51 | 2021 |
| A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin K Ernst, M Liebscher, S Mathea, A Granzhan, J Schmid, MR Popoff, ... Scientific reports 6 (1), 20301, 2016 | 48 | 2016 |
| Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms AU Malik, A Karapetsas, RS Nirujogi, S Mathea, D Chatterjee, P Pal, P Lis, ... Biochemical Journal 478 (3), 553-578, 2021 | 42 | 2021 |
| Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization J Gebel, LM Luh, D Coutandin, C Osterburg, F Löhr, B Schäfer, ... Cell Death & Differentiation 23 (12), 1930-1940, 2016 | 40 | 2016 |
| Pan-SMARCA/PB1 bromodomain inhibitors and their role in regulating adipogenesis M Wanior, F Preuss, X Ni, A Krämer, S Mathea, T Göbel, ... Journal of medicinal chemistry 63 (23), 14680-14699, 2020 | 27 | 2020 |
| Quantitative characterization of bivalent probes for a dual bromodomain protein, transcription initiation factor TFIID subunit 1 JL Suh, B Watts, JI Stuckey, JL Norris-Drouin, SH Cholensky, BM Dickson, ... Biochemistry 57 (14), 2140-2149, 2018 | 24 | 2018 |
| Kinase domain is a dynamic hub for driving LRRK2 allostery SS Taylor, P Kaila-Sharma, JH Weng, P Aoto, SH Schmidt, S Knapp, ... Frontiers in molecular neuroscience 13, 538219, 2020 | 23 | 2020 |
| Nucleotide binding, evolutionary insights, and interaction partners of the pseudokinase Unc-51-like kinase 4 F Preuss, D Chatterjee, S Mathea, S Shrestha, J St-Germain, M Saha, ... Structure 28 (11), 1184-1196. e6, 2020 | 22 | 2020 |
| Structure of the human protein kinase ZAK in complex with vemurafenib S Mathea, KR Abdul Azeez, E Salah, C Tallant, F Wolfreys, R Konietzny, ... ACS chemical biology 11 (6), 1595-1602, 2016 | 22 | 2016 |
| LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains JH Weng, PC Aoto, R Lorenz, J Wu, SH Schmidt, JT Manschwetus, ... PLoS biology 20 (2), e3001427, 2022 | 21 | 2022 |
| Identification of pyrimidine-based lead compounds for understudied kinases implicated in driving neurodegeneration DH Drewry, JK Annor-Gyamfi, CI Wells, JE Pickett, V Dederer, F Preuss, ... Journal of Medicinal Chemistry 65 (2), 1313-1328, 2021 | 21 | 2021 |
| Suppression of EGFR autophosphorylation by FKBP12 S Mathea, S Li, A Schierhorn, G Jahreis, C Schiene-Fischer Biochemistry 50 (50), 10844-10850, 2011 | 19 | 2011 |
