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James Scott Hale
James Scott Hale
Verified email at ccf.org
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Year
Preferential iron trafficking characterizes glioblastoma stem-like cells
DL Schonberg, TE Miller, Q Wu, WA Flavahan, NK Das, JS Hale, ...
Cancer cell 28 (4), 441-455, 2015
3142015
Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression
JS Hale, B Otvos, M Sinyuk, AG Alvarado, M Hitomi, K Stoltz, Q Wu, ...
Stem cells 32 (7), 1746-1758, 2014
2482014
Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion
B Otvos, DJ Silver, EE Mulkearns-Hubert, AG Alvarado, SM Turaga, ...
Stem cells 34 (8), 2026-2039, 2016
2422016
Laminin alpha 2 enables glioblastoma stem cell growth
JD Lathia, M Li, PE Hall, J Gallagher, JS Hale, Q Wu, M Venere, E Levy, ...
Annals of neurology 72 (5), 766-778, 2012
1882012
Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis
TJ Alban, AG Alvarado, MD Sorensen, D Bayik, J Volovetz, E Serbinowski, ...
JCI insight 3 (21), 2018
1852018
Glioblastoma cancer stem cells evade innate immune suppression of self-renewal through reduced TLR4 expression
AG Alvarado, PS Thiagarajan, EE Mulkearns-Hubert, DJ Silver, JS Hale, ...
Cell stem cell 20 (4), 450-461. e4, 2017
1842017
The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1
MN O'Leary, KH Schreiber, Y Zhang, ACE Duc, S Rao, JS Hale, ...
PLoS genetics 9 (8), e1003708, 2013
1392013
Differential connexin function enhances self-renewal in glioblastoma
M Hitomi, LP Deleyrolle, EE Mulkearns-Hubert, A Jarrar, M Li, M Sinyuk, ...
Cell reports 11 (7), 1031-1042, 2015
1262015
Brain cancer stem cells in adults and children: cell biology and therapeutic implications
TJ Abou-Antoun, JS Hale, JD Lathia, SM Dombrowski
Neurotherapeutics 14 (2), 372-384, 2017
1082017
Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair
M Li, JS Hale, JN Rich, RM Ransohoff, JD Lathia
Trends in neurosciences 35 (10), 619-628, 2012
1062012
CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors
C Saygin, A Wiechert, VS Rao, R Alluri, E Connor, PS Thiagarajan, ...
Journal of Experimental Medicine 214 (9), 2715-2732, 2017
932017
High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor
JD Lathia, M Li, M Sinyuk, AG Alvarado, WA Flavahan, K Stoltz, ...
Cell reports 6 (1), 117-129, 2014
922014
Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches
S Shakya, AD Gromovsky, JS Hale, AM Knudsen, B Prager, LC Wallace, ...
Acta Neuropathologica Communications 9 (1), 101, 2021
872021
Development of a fluorescent reporter system to delineate cancer stem cells in triple-negative breast cancer
PS Thiagarajan, M Hitomi, JS Hale, AG Alvarado, B Otvos, M Sinyuk, ...
Stem cells 33 (7), 2114-2125, 2015
862015
Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase
PS Thiagarajan, M Sinyuk, SM Turaga, EE Mulkearns-Hubert, JS Hale, ...
Nature communications 9 (1), 578, 2018
842018
Cisplatin induces stemness in ovarian cancer
A Wiechert, C Saygin, PS Thiagarajan, VS Rao, JS Hale, N Gupta, ...
Oncotarget 7 (21), 30511, 2016
732016
Lysophosphatidic acid suppresses endothelial cell CD36 expression and promotes angiogenesis via a PKD-1–dependent signaling pathway
B Ren, J Hale, S Srikanthan, RL Silverstein
Blood, The Journal of the American Society of Hematology 117 (22), 6036-6045, 2011
672011
ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells
A Jimenez-Pascual, JS Hale, A Kordowski, J Pugh, DJ Silver, D Bayik, ...
Cancer discovery 9 (11), 1574-1589, 2019
652019
The malignant social network: cell-cell adhesion and communication in cancer stem cells
JS Hale, M Li, JD Lathia
Cell adhesion & migration 6 (4), 346-355, 2012
622012
Phage display discovery of novel molecular targets in glioblastoma-initiating cells
JK Liu, D Lubelski, DL Schonberg, Q Wu, JS Hale, WA Flavahan, ...
Cell Death & Differentiation 21 (8), 1325-1339, 2014
432014
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