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Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling MA Daniels, E Teixeiro, J Gill, B Hausmann, D Roubaty, K Holmberg, ... Nature 444 (7120), 724-729, 2006 | 717 | 2006 |
Delta-like 4 is indispensable in thymic environment specific for T cell development K Hozumi, C Mailhos, N Negishi, K Hirano, T Yahata, K Ando, S Zuklys, ... The Journal of experimental medicine 205 (11), 2507-2513, 2008 | 476 | 2008 |
β cells are responsible for CXCR3-mediated T-cell infiltration in insulitis S Frigerio, T Junt, B Lu, C Gerard, U Zumsteg, GA Holländer, L Piali Nature medicine 8 (12), 1414-1420, 2002 | 394 | 2002 |
Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia SN Sansom, N Shikama-Dorn, S Zhanybekova, G Nusspaumer, ... Genome research 24 (12), 1918-1931, 2014 | 361 | 2014 |
Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes GA Holländer, B Wang, A Nichogiannopoulou, PP Platenburg, ... Nature 373 (6512), 350-353, 1995 | 351 | 1995 |
Generation of a complete thymic microenvironment by MTS24+ thymic epithelial cells J Gill, M Malin, GA Holländer, R Boyd Nature immunology 3 (7), 635-642, 2002 | 350 | 2002 |
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development Y Lei, AM Ripen, N Ishimaru, I Ohigashi, T Nagasawa, LT Jeker, MR Bösl, ... Journal of Experimental Medicine 208 (2), 383-394, 2011 | 344 | 2011 |
Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy … S Zuklys, G Balciunaite, A Agarwal, E Fasler-Kan, E Palmer, ... The Journal of Immunology 165 (4), 1976-1983, 2000 | 331 | 2000 |
Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice G Balciunaite, MP Keller, E Balciunaite, L Piali, S Zuklys, YD Mathieu, ... Nature immunology 3 (11), 1102-1108, 2002 | 330 | 2002 |
Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae D Leppert, SL Leib, C Grygar, KM Miller, UB Schaad, GA Holländer Clinical Infectious Diseases 31 (1), 80-84, 2000 | 321 | 2000 |
Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen M Alimohammadi, P Björklund, Å Hallgren, N Pöntynen, G Szinnai, ... New England Journal of Medicine 358 (10), 1018-1028, 2008 | 307 | 2008 |
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Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology BE Bierer, G Holländer, D Fruman, SJ Burakoff Current opinion in immunology 5 (5), 763-773, 1993 | 281 | 1993 |
Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity M Irla, S Hugues, J Gill, T Nitta, Y Hikosaka, IR Williams, FX Hubert, ... Immunity 29 (3), 451-463, 2008 | 279 | 2008 |
Monoallelic expression of the interleukin-2 locus GA Hollander, S Zuklys, C Morel, E Mizoguchi, K Mobisson, S Simpson, ... Science 279 (5359), 2118-2121, 1998 | 277 | 1998 |
Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells SW Rossi, LT Jeker, T Ueno, S Kuse, MP Keller, S Zuklys, AV Gudkov, ... Blood 109 (9), 3803-3811, 2007 | 247 | 2007 |
Thymic T-cell development in allogeneic stem cell transplantation W Krenger, BR Blazar, GA Holländer Blood, The Journal of the American Society of Hematology 117 (25), 6768-6776, 2011 | 243 | 2011 |
Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease S Rossi, BR Blazar, CL Farrell, DM Danilenko, DL Lacey, KI Weinberg, ... Blood, The Journal of the American Society of Hematology 100 (2), 682-691, 2002 | 242 | 2002 |
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