J. Silvio Gutkind,  Ph.D.
J. Silvio Gutkind, Ph.D.
UCSD, Distinguished Professor and Chair, Dept. Pharmacology, AD Basic Science Moores Cancer Center
Verified email at - Homepage
Cited by
Cited by
The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway
OA Coso, M Chiariello, JC Yu, H Teramoto, P Crespo, N Xu, T Miki, ...
Cell 81 (7), 1137-1146, 1995
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
O Cuvillier, G Pirianov, B Kleuser, PG Vanek, OA Coso, JS Gutkind, ...
Nature 381 (6585), 800-803, 1996
G-protein-coupled receptors and cancer
RT Dorsam, JS Gutkind
Nature reviews cancer 7 (2), 79-94, 2007
Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.
S Miyamoto, H Teramoto, OA Coso, JS Gutkind, PD Burbelo, SK Akiyama, ...
The Journal of cell biology 131 (3), 791-805, 1995
G-protein-coupled receptors and signaling networks: emerging paradigms
MJ Marinissen, JS Gutkind
Trends in pharmacological sciences 22 (7), 368-376, 2001
VEGF controls endothelial-cell permeability by promoting the β-arrestin-dependent endocytosis of VE-cadherin
J Gavard, JS Gutkind
Nature cell biology 8 (11), 1223-1234, 2006
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin--catenin signaling axis
MD Castellone, H Teramoto, BO Williams, KM Druey, JS Gutkind
Science 310 (5753), 1504-1510, 2005
Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits
P Crespo, N Xu, WF Simonds, JS Gutkind
Nature 369 (6479), 418-420, 1994
The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades
JS Gutkind
Journal of Biological Chemistry 273 (4), 1839-1842, 1998
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator
C Bais, B Santomasso, O Coso, L Arvanitakis, EG Raaka, JS Gutkind, ...
Nature 391 (6662), 86-89, 1998
Targeted Killing of Cancer Cells in Vivo and in Vitro with EGF-Directed Carbon Nanotube-Based Drug Delivery
AA Bhirde, V Patel, J Gavard, G Zhang, AA Sousa, A Masedunskas, ...
ACS nano 3 (2), 307-316, 2009
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors.
S Miyamoto, H Teramoto, JS Gutkind, KM Yamada
The Journal of cell biology 135 (6), 1633-1642, 1996
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
P Crespo, KE Schuebel, AA Ostrom, JS Gutkind, XR Bustelo
Nature 385 (6612), 169-172, 1997
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ
M Lopez-Ilasaca, P Crespo, PG Pellici, JS Gutkind, R Wetzker
Science 275 (5298), 394-397, 1997
Augmented Wnt signaling in a mammalian model of accelerated aging
H Liu, MM Fergusson, RM Castilho, J Liu, L Cao, J Chen, D Malide, ...
Science 317 (5839), 803-806, 2007
Carbon nanotube amplification strategies for highly sensitive immunodetection of cancer biomarkers
X Yu, B Munge, V Patel, G Jensen, A Bhirde, JD Gong, SN Kim, ...
Journal of the American Chemical Society 128 (34), 11199-11205, 2006
G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension
A Wirth, Z Beny, M Lukasova, B Leutgeb, N Wettschureck, S Gorbey, ...
Nature medicine 14 (1), 64-68, 2008
Cbl-b regulates the CD28 dependence of T-cell activation
YJ Chiang, HK Kole, K Brown, M Naramura, S Fukuhara, RJ Hu, IK Jang, ...
Nature 403 (6766), 216-220, 2000
Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer
JF Rusling, CV Kumar, JS Gutkind, V Patel
Analyst 135 (10), 2496-2511, 2010
Regulation of reactive-oxygen-species generation in fibroblasts by Rac 1
M Sundaresan, ZX Yu, VJ Ferrans, DJ Sulciner, S GUTKIND, KJ IRANI, ...
Biochemical Journal 318 (2), 379-382, 1996
The system can't perform the operation now. Try again later.
Articles 1–20