| Distinguishing genetic correlation from causation across 52 diseases and complex traits LJ O’Connor, AL Price Nature genetics 50 (12), 1728-1734, 2018 | 402 | 2018 |
| Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels A Tin, J Marten, VL Halperin Kuhns, Y Li, M Wuttke, H Kirsten, KB Sieber, ... Nature genetics 51 (10), 1459-1474, 2019 | 357 | 2019 |
| Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank Z Zhu, Y Guo, H Shi, CL Liu, RA Panganiban, W Chung, LJ O'Connor, ... Journal of Allergy and Clinical Immunology 145 (2), 537-549, 2020 | 323 | 2020 |
| Functionally informed fine-mapping and polygenic localization of complex trait heritability O Weissbrod, F Hormozdiari, C Benner, R Cui, J Ulirsch, S Gazal, ... Nature genetics 52 (12), 1355-1363, 2020 | 291 | 2020 |
| Quantifying genetic effects on disease mediated by assayed gene expression levels DW Yao, LJ O’connor, AL Price, A Gusev Nature genetics 52 (6), 626-633, 2020 | 288 | 2020 |
| Extreme polygenicity of complex traits is explained by negative selection LJ O'Connor, AP Schoech, F Hormozdiari, S Gazal, N Patterson, AL Price The American Journal of Human Genetics 105 (3), 456-476, 2019 | 254 | 2019 |
| Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits F Hormozdiari, S Gazal, B Van De Geijn, HK Finucane, CJT Ju, PR Loh, ... Nature genetics 50 (7), 1041-1047, 2018 | 176 | 2018 |
| Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection AP Schoech, DM Jordan, PR Loh, S Gazal, LJ O’Connor, DJ Balick, ... Nature communications 10 (1), 790, 2019 | 142 | 2019 |
| Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity S Gazal, O Weissbrod, F Hormozdiari, KK Dey, J Nasser, KA Jagadeesh, ... Nature Genetics 54 (6), 827-836, 2022 | 121 | 2022 |
| Polygenic architecture of rare coding variation across 394,783 exomes DJ Weiner, A Nadig, KA Jagadeesh, KK Dey, BM Neale, EB Robinson, ... Nature 614 (7948), 492-499, 2023 | 118 | 2023 |
| Functional architectures of local and distal regulation of gene expression in multiple human tissues X Liu, HK Finucane, A Gusev, G Bhatia, S Gazal, L O’Connor, ... The American Journal of Human Genetics 100 (4), 605-616, 2017 | 92 | 2017 |
| The distribution of common-variant effect sizes LJ O’Connor Nature genetics 53 (8), 1243-1249, 2021 | 73 | 2021 |
| Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk YA Reshef, HK Finucane, DR Kelley, A Gusev, D Kotliar, JC Ulirsch, ... Nature genetics 50 (10), 1483-1493, 2018 | 72 | 2018 |
| Genes with high network connectivity are enriched for disease heritability SS Kim, C Dai, F Hormozdiari, B van de Geijn, S Gazal, Y Park, ... The American Journal of Human Genetics 104 (5), 896-913, 2019 | 62 | 2019 |
| Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p DJ Weiner, E Ling, S Erdin, DJC Tai, R Yadav, J Grove, JM Fu, A Nadig, ... Nature genetics 54 (11), 1630-1639, 2022 | 34 | 2022 |
| High-dimensional phenotyping to define the genetic basis of cellular morphology M Tegtmeyer, J Arora, S Asgari, BA Cimini, A Nadig, E Peirent, ... Nature Communications 15 (1), 347, 2024 | 29 | 2024 |
| Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies P Salehi Nowbandegani, AW Wohns, JL Ballard, ES Lander, ... Nature Genetics 55 (9), 1494-1502, 2023 | 24 | 2023 |
| Significance testing for small annotations in stratified LD-Score regression KC Tashman, R Cui, LJ O’Connor, BM Neale, HK Finucane medRxiv, 2021.03. 13.21249938, 2021 | 22 | 2021 |
| German Chronic Kidney Disease Study; Lifelines Cohort Study; VA Million Veteran Program. Target genes, variants, tissues and transcriptional pathways influencing human serum … A Tin, J Marten, VL Halperin Kuhns, Y Li, M Wuttke, H Kirsten, KB Sieber, ... Nat Genet 51 (10), 1459-1474, 2019 | 21 | 2019 |
| Partitioning gene-mediated disease heritability without eQTLs DJ Weiner, S Gazal, EB Robinson, LJ O’Connor The American Journal of Human Genetics 109 (3), 405-416, 2022 | 17 | 2022 |
