| Viral quasispecies evolution E Domingo, J Sheldon, C Perales Microbiology and Molecular Biology Reviews 76 (2), 159-216, 2012 | 1114 | 2012 |
| Viruses as quasispecies: biological implications E Domingo, V Martin, C Perales, A Grande-Perez, J Garcia-Arriaza, ... Quasispecies: concept and implications for virology, 51-82, 2006 | 342 | 2006 |
| Viral quasispecies E Domingo, C Perales PLoS genetics 15 (10), e1008271, 2019 | 321 | 2019 |
| HIV-1 protease cleaves eukaryotic initiation factor 4G and inhibits cap-dependent translation I Ventoso, R Blanco, C Perales, L Carrasco Proceedings of the National Academy of Sciences 98 (23), 12966-12971, 2001 | 164 | 2001 |
| Virus evolution E Domingo Fields virology 5, 391-422, 2007 | 127 | 2007 |
| Viral quasispecies complexity measures J Gregori, C Perales, F Rodriguez-Frias, JI Esteban, J Quer, E Domingo Virology 493, 227-237, 2016 | 120 | 2016 |
| Viral genome segmentation can result from a trade-off between genetic content and particle stability S Ojosnegros, J Garcia-Arriaza, C Escarmis, SC Manrubia, C Perales, ... PLoS genetics 7 (3), e1001344, 2011 | 115 | 2011 |
| Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants C Perales, R Mateo, MG Mateu, E Domingo Journal of molecular biology 369 (4), 985-1000, 2007 | 112 | 2007 |
| High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods J Quer, J Gregori, F Rodríguez-Frias, M Buti, A Madejon, ... Journal of clinical microbiology 53 (1), 219-226, 2015 | 108 | 2015 |
| A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape R Agudo, C Ferrer-Orta, A Arias, I de la Higuera, C Perales, ... PLoS pathogens 6 (8), e1001072, 2010 | 106 | 2010 |
| Mutation rates, mutation frequencies, and proofreading-repair activities in RNA virus genetics E Domingo, C García-Crespo, R Lobo-Vega, C Perales Viruses 13 (9), 1882, 2021 | 103 | 2021 |
| GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 E Pairo-Castineira, K Rawlik, AD Bretherick, T Qi, Y Wu, I Nassiri, ... Nature 617 (7962), 764-768, 2023 | 85 | 2023 |
| Lethal mutagenesis of hepatitis C virus induced by favipiravir AI De Ávila, I Gallego, ME Soria, J Gregori, J Quer, JI Esteban, CM Rice, ... PloS one 11 (10), e0164691, 2016 | 84 | 2016 |
| Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus J Sheldon, NM Beach, E Moreno, I Gallego, D Piñeiro, E Martínez-Salas, ... Journal of virology 88 (20), 12098-12111, 2014 | 84 | 2014 |
| Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype C Perales, NM Beach, I Gallego, ME Soria, J Quer, JI Esteban, C Rice, ... Journal of virology 87 (13), 7593-7607, 2013 | 83 | 2013 |
| Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis AM Ortega-Prieto, J Sheldon, A Grande-Pérez, H Tejero, J Gregori, J Quer, ... PloS one 8 (8), e71039, 2013 | 81 | 2013 |
| Quasispecies as a matter of fact: viruses and beyond S Ojosnegros, C Perales, A Mas, E Domingo Virus research 162 (1-2), 203-215, 2011 | 81 | 2011 |
| Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections C Perales, R Agudo, H Tejero, SC Manrubia, E Domingo PLoS pathogens 5 (11), e1000658, 2009 | 81 | 2009 |
| Quasispecies and virus E Domingo, C Perales European Biophysics Journal 47 (4), 443-457, 2018 | 77 | 2018 |
| Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants J Gregori, JI Esteban, M Cubero, D Garcia-Cehic, C Perales, R Casillas, ... PloS one 8 (12), e83361, 2013 | 73 | 2013 |
