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John M Heddleston
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The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
JM Heddleston, Z Li, RE McLendon, AB Hjelmeland, JN Rich
Cell cycle 8 (20), 3274-3284, 2009
9162009
Integrin alpha 6 regulates glioblastoma stem cells
JD Lathia, J Gallagher, JM Heddleston, J Wang, CE Eyler, J MacSwords, ...
Cell stem cell 6 (5), 421-432, 2010
7792010
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ...
Science 359 (6378), eaao6047, 2018
6582018
Hypoxia inducible factors in cancer stem cells
JM Heddleston, Z Li, JD Lathia, S Bao, AB Hjelmeland, JN Rich
British journal of cancer 102 (5), 789-795, 2010
5792010
HIF induces human embryonic stem cell markers in cancer cells
J Mathieu, Z Zhang, W Zhou, AJ Wang, JM Heddleston, CMA Pinna, ...
Cancer research 71 (13), 4640-4652, 2011
5782011
Acidic stress promotes a glioma stem cell phenotype
AB Hjelmeland, Q Wu, JM Heddleston, GS Choudhary, J MacSwords, ...
Cell Death & Differentiation 18 (5), 829-840, 2011
4512011
High-speed coherent Raman fingerprint imaging of biological tissues
CH Camp Jr, YJ Lee, JM Heddleston, CM Hartshorn, ARH Walker, ...
Nature photonics 8 (8), 627-634, 2014
4442014
Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth
H Wang, JD Lathia, Q Wu, J Wang, Z Li, JM Heddleston, CE Eyler, ...
Stem cells 27 (10), 2393-2404, 2009
3862009
Deadly teamwork: neural cancer stem cells and the tumor microenvironment
JD Lathia, JM Heddleston, M Venere, JN Rich
Cell stem cell 8 (5), 482-485, 2011
2902011
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3
OA Guryanova, Q Wu, L Cheng, JD Lathia, Z Huang, J Yang, ...
Cancer cell 19 (4), 498-511, 2011
2722011
Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions
JD Lathia, M Hitomi, J Gallagher, SP Gadani, J Adkins, A Vasanji, L Liu, ...
Cell death & disease 2 (9), e200-e200, 2011
2092011
Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation
M Fritzsche, RA Fernandes, VT Chang, H Colin-York, MP Clausen, ...
Science advances 3 (6), e1603032, 2017
1582017
Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential
JM Heddleston, Q Wu, M Rivera, S Minhas, JD Lathia, AE Sloan, ...
Cell Death & Differentiation 19 (3), 428-439, 2012
1492012
Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth
AB Hjelmeland, Q Wu, S Wickman, C Eyler, J Heddleston, Q Shi, ...
PLoS biology 8 (2), e1000319, 2010
1402010
Glioma stem cell maintenance: the role of the microenvironment
J M Heddleston, M Hitomi, M Venere, W A Flavahan, K Yang, Y Kim, ...
Current pharmaceutical design 17 (23), 2386-2401, 2011
1052011
A moving source of matrix components is essential for de novo basement membrane formation
Y Matsubayashi, A Louani, A Dragu, BJ Sanchez-Sanchez, ...
Current Biology 27 (22), 3526-3534. e4, 2017
1002017
Interfacial actin protrusions mechanically enhance killing by cytotoxic T cells
F Tamzalit, MS Wang, W Jin, M Tello-Lafoz, V Boyko, JM Heddleston, ...
Science immunology 4 (33), eaav5445, 2019
992019
Actin cables and comet tails organize mitochondrial networks in mitosis
AS Moore, SM Coscia, CL Simpson, FE Ortega, EC Wait, JM Heddleston, ...
Nature 591 (7851), 659-664, 2021
922021
Macropinosome formation by tent pole ruffling in macrophages
ND Condon, JM Heddleston, TL Chew, L Luo, PS McPherson, ...
Journal of Cell Biology 217 (11), 3873-3885, 2018
922018
Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis
SR Barger, NS Reilly, MS Shutova, Q Li, P Maiuri, JM Heddleston, ...
Nature communications 10 (1), 1249, 2019
772019
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