The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype JM Heddleston, Z Li, RE McLendon, AB Hjelmeland, JN Rich Cell cycle 8 (20), 3274-3284, 2009 | 947 | 2009 |
Integrin alpha 6 regulates glioblastoma stem cells JD Lathia, J Gallagher, JM Heddleston, J Wang, CE Eyler, J MacSwords, ... Cell stem cell 6 (5), 421-432, 2010 | 809 | 2010 |
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ... Science 359 (6378), eaao6047, 2018 | 786 | 2018 |
Hypoxia inducible factors in cancer stem cells JM Heddleston, Z Li, JD Lathia, S Bao, AB Hjelmeland, JN Rich British journal of cancer 102 (5), 789-795, 2010 | 601 | 2010 |
HIF induces human embryonic stem cell markers in cancer cells J Mathieu, Z Zhang, W Zhou, AJ Wang, JM Heddleston, CMA Pinna, ... Cancer research 71 (13), 4640-4652, 2011 | 600 | 2011 |
Acidic stress promotes a glioma stem cell phenotype AB Hjelmeland, Q Wu, JM Heddleston, GS Choudhary, J MacSwords, ... Cell Death & Differentiation 18 (5), 829-840, 2011 | 484 | 2011 |
High-speed coherent Raman fingerprint imaging of biological tissues CH Camp Jr, YJ Lee, JM Heddleston, CM Hartshorn, ARH Walker, ... Nature photonics 8 (8), 627-634, 2014 | 479 | 2014 |
Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth H Wang, JD Lathia, Q Wu, J Wang, Z Li, JM Heddleston, CE Eyler, ... Stem cells 27 (10), 2393-2404, 2009 | 410 | 2009 |
Deadly teamwork: neural cancer stem cells and the tumor microenvironment JD Lathia, JM Heddleston, M Venere, JN Rich Cell stem cell 8 (5), 482-485, 2011 | 301 | 2011 |
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3 OA Guryanova, Q Wu, L Cheng, JD Lathia, Z Huang, J Yang, ... Cancer cell 19 (4), 498-511, 2011 | 282 | 2011 |
Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions JD Lathia, M Hitomi, J Gallagher, SP Gadani, J Adkins, A Vasanji, L Liu, ... Cell death & disease 2 (9), e200-e200, 2011 | 216 | 2011 |
Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation M Fritzsche, RA Fernandes, VT Chang, H Colin-York, MP Clausen, ... Science advances 3 (6), e1603032, 2017 | 174 | 2017 |
Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential JM Heddleston, Q Wu, M Rivera, S Minhas, JD Lathia, AE Sloan, ... Cell Death & Differentiation 19 (3), 428-439, 2012 | 149 | 2012 |
Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth AB Hjelmeland, Q Wu, S Wickman, C Eyler, J Heddleston, Q Shi, ... PLoS biology 8 (2), e1000319, 2010 | 144 | 2010 |
Actin cables and comet tails organize mitochondrial networks in mitosis AS Moore, SM Coscia, CL Simpson, FE Ortega, EC Wait, JM Heddleston, ... Nature 591 (7851), 659-664, 2021 | 124 | 2021 |
Interfacial actin protrusions mechanically enhance killing by cytotoxic T cells F Tamzalit, MS Wang, W Jin, M Tello-Lafoz, V Boyko, JM Heddleston, ... Science immunology 4 (33), eaav5445, 2019 | 115 | 2019 |
A moving source of matrix components is essential for de novo basement membrane formation Y Matsubayashi, A Louani, A Dragu, BJ Sanchez-Sanchez, ... Current Biology 27 (22), 3526-3534. e4, 2017 | 109 | 2017 |
Macropinosome formation by tent pole ruffling in macrophages ND Condon, JM Heddleston, TL Chew, L Luo, PS McPherson, ... Journal of Cell Biology 217 (11), 3873-3885, 2018 | 107 | 2018 |
Glioma stem cell maintenance: the role of the microenvironment J M Heddleston, M Hitomi, M Venere, W A Flavahan, K Yang, Y Kim, ... Current pharmaceutical design 17 (23), 2386-2401, 2011 | 107 | 2011 |
Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis Y Sato, L Hilbert, H Oda, Y Wan, JM Heddleston, TL Chew, V Zaburdaev, ... Development 146 (19), dev179127, 2019 | 88 | 2019 |