| Molecular basis of agonism and antagonism in the oestrogen receptor AM Brzozowski, ACW Pike, Z Dauter, RE Hubbard, T Bonn, O Engström, ... Nature 389 (6652), 753-758, 1997 | 4208 | 1997 |
| Estrogen receptors: how do they signal and what are their targets N Heldring, A Pike, S Andersson, J Matthews, G Cheng, J Hartman, ... Physiological reviews 87 (3), 905-931, 2007 | 2374 | 2007 |
| Structure of the ligand‐binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist ACW Pike, AM Brzozowski, RE Hubbard, T Bonn, AG Thorsell, ... The EMBO journal, 1999 | 1307 | 1999 |
| Structural insights into the mode of action of a pure antiestrogen ACW Pike, AM Brzozowski, J Walton, RE Hubbard, AG Thorsell, YL Li, ... Structure 9 (2), 145-153, 2001 | 471 | 2001 |
| K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac YY Dong, ACW Pike, A Mackenzie, C McClenaghan, P Aryal, L Dong, ... Science 347 (6227), 1256-1259, 2015 | 333 | 2015 |
| Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases P Canning, CDO Cooper, T Krojer, JW Murray, ACW Pike, A Chaikuad, ... Journal of Biological Chemistry 288 (11), 7803-7814, 2013 | 310 | 2013 |
| Structure of the CaMKIIδ/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation P Rellos, ACW Pike, FH Niesen, E Salah, WH Lee, F Von Delft, S Knapp PLoS biology 8 (7), e1000426, 2010 | 291 | 2010 |
| Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states CA Shintre, ACW Pike, Q Li, JI Kim, AJ Barr, S Goubin, L Shrestha, J Yang, ... Proceedings of the National Academy of Sciences 110 (24), 9710-9715, 2013 | 282 | 2013 |
| Crystal structures of guinea-pig, goat and bovine α-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase ACW Pike, K Brew, KR Acharya Structure 4 (6), 691-703, 1996 | 270 | 1996 |
| A structural biologist's view of the oestrogen receptor ACW Pike, AM Brzozowski, RE Hubbard The Journal of steroid biochemistry and molecular biology 74 (5), 261-268, 2000 | 224 | 2000 |
| Structure of human factor VIIa and its implications for the triggering of blood coagulation ACW Pike, AM Brzozowski, SM Roberts, OH Olsen, E Persson Proceedings of the National Academy of Sciences 96 (16), 8925-8930, 1999 | 209 | 1999 |
| Interaction of transcriptional intermediary factor 2 nuclear receptor box peptides with the coactivator binding site of estrogen receptor α A Wärnmark, E Treuter, JÅ Gustafsson, RE Hubbard, AM Brzozowski, ... Journal of Biological Chemistry 277 (24), 21862-21868, 2002 | 207 | 2002 |
| Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2) M Grieben, ACW Pike, CA Shintre, E Venturi, S El-Ajouz, A Tessitore, ... Nature structural & molecular biology 24 (2), 114-122, 2017 | 203 | 2017 |
| Activation segment dimerization: a mechanism for kinase autophosphorylation of non‐consensus sites ACW Pike, P Rellos, FH Niesen, A Turnbull, AW Oliver, SA Parker, ... The EMBO journal 27 (4), 704-714, 2008 | 184 | 2008 |
| Structure and regulation of the human Nek2 centrosomal kinase P Rellos, FJ Ivins, JE Baxter, A Pike, TJ Nott, DM Parkinson, S Das, ... Journal of Biological Chemistry 282 (9), 6833-6842, 2007 | 148 | 2007 |
| Distinct recognition modes of FXXLF and LXXLL motifs by the androgen receptor HJ Dubbink, R Hersmus, CS Verma, HAGM van der Korput, ... Molecular endocrinology 18 (9), 2132-2150, 2004 | 143 | 2004 |
| The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K SR Bushell, ACW Pike, ME Falzone, NJG Rorsman, CM Ta, RA Corey, ... Nature communications 10 (1), 3956, 2019 | 142 | 2019 |
| Lessons learnt from structural studies of the oestrogen receptor ACW Pike Best Practice & Research Clinical Endocrinology & Metabolism 20 (1), 1-14, 2006 | 142 | 2006 |
| Structure of the human RECQ1 helicase reveals a putative strand-separation pin ACW Pike, B Shrestha, V Popuri, N Burgess-Brown, L Muzzolini, ... Proceedings of the National Academy of Sciences 106 (4), 1039-1044, 2009 | 137 | 2009 |
| Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2 M Wilkes, MG Madej, L Kreuter, D Rhinow, V Heinz, S De Sanctis, ... Nature structural & molecular biology 24 (2), 123-130, 2017 | 136 | 2017 |
Roderick HubbardUniversity of York and Vernalis (R&D) LtdVerified email at york.ac.uk
