Marcel Kool

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Stefan M. PfisterProfessor of Pediatrics, Hopp-Children´s Cancer Center Heidelberg (KiTZ)Verified email at kitz-heidelberg.de
Paul A. NorthcottSt. Jude Children's Research HospitalVerified email at stjude.org
David T. W. JonesHead of Division - 'Pediatric Glioma Research', DKFZVerified email at dkfz.de
Michael TaylorTexas Children's Hospital, Baylor College of MedicineVerified email at bcm.edu
Torsten PietschProfessor and Chairman, Institute of Neuropathology, University of BonnVerified email at uni-bonn.de
K PajtlerVerified email at dkfz.de
Yoon-Jae ChoProfessor of PediatricsVerified email at ohsu.edu
Scott L. PomeroyBronson Crothers Professor of Neurology, Harvard Medical SchoolVerified email at childrens.harvard.edu
Lukas ChavezAssociate Professor, Department of Medicine, University of California, San Diego (UCSD)Verified email at ucsd.edu
Frank BaasLUMCVerified email at lumc.nl
Just VlakProfessor of Virology, Wageningen UniversityVerified email at wur.nl
Vijay RamaswamyHospital for Sick Children, University of TorontoVerified email at sickkids.ca
Jan KosterGroupleader Bioinformatics, AUMC, location AMCVerified email at amsterdamumc.nl
Jens BuntSenior Researcher at Princess Máxima Center for Pediatric OncologyVerified email at prinsesmaximacentrum.nl
Steve CliffordProfessor of Paediatric Oncology & Director, Newcastle University Centre for CancerVerified email at ncl.ac.uk
James M. OlsonSeattle Children's Research InstituteVerified email at seattlechildrens.org
Nada JabadoMcGill Univ.Verified email at mcgill.ca
Jan Molenaar-Verified email at prinsesmaximacentrum.nl
Alexander EGGERMONTPrincess Maxima Center & University Medical Center Utrecht, Netherlands alexander.eggermontVerified email at prinsesmaximacentrum.nl
Leendert LooijengaProfessor Translational Patho-OncologyVerified email at prinsesmaximacentrum.nl

Marcel Kool

PI, Hopp Children's Cancer Center Heidelberg & Princess Maxima Center Pediatric Oncology Utrecht

Verified email at dkfz.de

Pediatric Neurooncology cancer genomics brain tumors medulloblastoma ependymoma


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Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... nature 500 (7463), 415-421, 2013	10368	2013
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012	2754	2012
DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018	2515	2018
A family of drug transporters: the multidrug resistance-associated proteins P Borst, R Evers, M Kool, J Wijnholds Journal of the National Cancer Institute 92 (16), 1295-1302, 2000	2369	2000
Molecular subgroups of medulloblastoma: the current consensus MD Taylor, PA Northcott, A Korshunov, M Remke, YJ Cho, SC Clifford, ... Acta neuropathologica 123, 465-472, 2012	2147	2012
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012	2020	2012
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020	1969*	2020
The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018	1439	2018
Analysis of Expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, Homologues of the Multidrug Resistance-associated Protein Gene (MRP1), in Human … M Kool, M de Haas, GL Scheffer, RJ Scheper, MJT van Eijk, JA Juijn, ... Cancer research 57 (16), 3537-3547, 1997	1181	1997
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ... Acta neuropathologica 123, 473-484, 2012	1168	2012
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015	1154	2015
The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017	1041	2017
K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ... Acta neuropathologica 124, 439-447, 2012	1018	2012
Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012	997	2012
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012	982	2012
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ... Cell 148 (1), 59-71, 2012	967	2012
The multidrug resistance protein family P Borst, R Evers, M Kool, J Wijnholds Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 347-357, 1999	907	1999
New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016	885	2016
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ... Journal of clinical oncology 29 (11), 1424-1430, 2011	857	2011
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013	842	2013

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