| Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits A Caspi, AR Hariri, A Holmes, R Uher, TE Moffitt American journal of Psychiatry 167 (5), 509-527, 2010 | 1773 | 2010 |
| The ascent of mouse: advances in modelling human depression and anxiety JF Cryan, A Holmes Nature reviews Drug discovery 4 (9), 775-790, 2005 | 1495 | 2005 |
| Genetics of emotional regulation: the role of the serotonin transporter in neural function AR Hariri, A Holmes Trends in cognitive sciences 10 (4), 182-191, 2006 | 869 | 2006 |
| Animal models of anxiety: an ethological perspective RJ Rodgers, BJ Cao, A Dalvi, A Holmes Brazilian journal of medical and biological research 30, 289-304, 1997 | 867 | 1997 |
| The neural basis of reversal learning: An updated perspective A Izquierdo, JL Brigman, AK Radke, PH Rudebeck, A Holmes Neuroscience 345, 12-26, 2017 | 663 | 2017 |
| Stress-induced prefrontal reorganization and executive dysfunction in rodents A Holmes, CL Wellman Neuroscience & Biobehavioral Reviews 33 (6), 773-783, 2009 | 579 | 2009 |
| Brief uncontrollable stress causes dendritic retraction in infralimbic cortex and resistance to fear extinction in mice A Izquierdo, CL Wellman, A Holmes Journal of Neuroscience 26 (21), 5733-5738, 2006 | 541 | 2006 |
| Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders A Holmes, M Heilig, NMJ Rupniak, T Steckler, G Griebel Trends in pharmacological sciences 24 (11), 580-588, 2003 | 526 | 2003 |
| Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala CA Marcinkiewcz, CM Mazzone, G D’Agostino, LR Halladay, ... Nature 537 (7618), 97-101, 2016 | 473 | 2016 |
| Effects of repeated maternal separation on anxiety-and depression-related phenotypes in different mouse strains RA Millstein, A Holmes Neuroscience & Biobehavioral Reviews 31 (1), 3-17, 2007 | 467 | 2007 |
| Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders N Singewald, C Schmuckermair, N Whittle, A Holmes, KJ Ressler Pharmacology & therapeutics 149, 150-190, 2015 | 462 | 2015 |
| The touchscreen operant platform for testing learning and memory in rats and mice AE Horner, CJ Heath, M Hvoslef-Eide, BA Kent, CH Kim, SRO Nilsson, ... Nature protocols 8 (10), 1961-1984, 2013 | 443 | 2013 |
| Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression A Holmes, DL Murphy, JN Crawley Biological psychiatry 54 (10), 953-959, 2003 | 442 | 2003 |
| Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice CL Wellman, A Izquierdo, JE Garrett, KP Martin, J Carroll, R Millstein, ... Journal of Neuroscience 27 (3), 684-691, 2007 | 420 | 2007 |
| Stress and fear extinction S Maren, A Holmes Neuropsychopharmacology 41 (1), 58-79, 2016 | 419 | 2016 |
| Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning JL Brigman, T Wright, G Talani, S Prasad-Mulcare, S Jinde, GK Seabold, ... Journal of Neuroscience 30 (13), 4590-4600, 2010 | 408 | 2010 |
| Abnormal anxiety‐related behavior in serotonin transporter null mutant mice: the influence of genetic background A Holmes, Q Li, DL Murphy, E Gold, JN Crawley Genes, Brain and Behavior 2 (6), 365-380, 2003 | 382 | 2003 |
| Mice lacking the serotonin transporter exhibit 5-HT1A receptor-mediated abnormalities in tests for anxiety-like behavior A Holmes, RJ Yang, KP Lesch, JN Crawley, DL Murphy Neuropsychopharmacology 28 (12), 2077-2088, 2003 | 378 | 2003 |
| Early life genetic, epigenetic and environmental factors shaping emotionality in rodents A Holmes, AM le Guisquet, E Vogel, RA Millstein, S Leman, C Belzung Neuroscience & Biobehavioral Reviews 29 (8), 1335-1346, 2005 | 367 | 2005 |
| 50 years of hurdles and hope in anxiolytic drug discovery G Griebel, A Holmes Nature reviews Drug discovery 12 (9), 667-687, 2013 | 360 | 2013 |
JL BrigmanProfessor of Neurosciences, University of New Mexico SOMVerified email at salud.unm.edu
