| Multi-target-directed ligands to combat neurodegenerative diseases A Cavalli, ML Bolognesi, A Minarini, M Rosini, V Tumiatti, M Recanatini, ... Journal of medicinal chemistry 51 (3), 347-372, 2008 | 1314 | 2008 |
| Role of molecular dynamics and related methods in drug discovery M De Vivo, M Masetti, G Bottegoni, A Cavalli Journal of medicinal chemistry 59 (9), 4035-4061, 2016 | 1124 | 2016 |
| Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K+ channel blockers A Cavalli, E Poluzzi, F De Ponti, M Recanatini Journal of medicinal chemistry 45 (18), 3844-3853, 2002 | 496 | 2002 |
| Insight into the kinetic of amyloid β (1–42) peptide self‐aggregation: elucidation of inhibitors’ mechanism of action M Bartolini, C Bertucci, ML Bolognesi, A Cavalli, C Melchiorre, ... ChemBioChem 8 (17), 2152-2161, 2007 | 431 | 2007 |
| Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: an overview F De Ponti, E Poluzzi, A Cavalli, M Recanatini, N Montanaro Drug safety 25, 263-286, 2002 | 389 | 2002 |
| QT prolongation through hERG K+ channel blockade: Current knowledge and strategies for the early prediction during drug development M Recanatini, E Poluzzi, M Masetti, A Cavalli, F De Ponti Medicinal research reviews 25 (2), 133-166, 2005 | 349 | 2005 |
| 3-(4-{[Benzyl(methyl)amino]methyl}phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) Inhibits Both Acetylcholinesterase and Acetylcholinesterase-Induced β … L Piazzi, A Rampa, A Bisi, S Gobbi, F Belluti, A Cavalli, M Bartolini, ... Journal of medicinal chemistry 46 (12), 2279-2282, 2003 | 320 | 2003 |
| Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer’s disease ML Bolognesi, A Cavalli, L Valgimigli, M Bartolini, M Rosini, V Andrisano, ... Journal of medicinal chemistry 50 (26), 6446-6449, 2007 | 314 | 2007 |
| Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds L Piazzi, A Cavalli, F Colizzi, F Belluti, M Bartolini, F Mancini, ... Bioorganic & Medicinal Chemistry Letters 18 (1), 423-426, 2008 | 298 | 2008 |
| Neglected Tropical Diseases: Multi-Target-Directed Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania A Cavalli, ML Bolognesi Journal of Medicinal Chemistry 52 (23), 7339-7359, 2009 | 285 | 2009 |
| Molecular basis of cyclooxygenase enzymes (COXs) selective inhibition V Limongelli, M Bonomi, L Marinelli, FL Gervasio, A Cavalli, E Novellino, ... Proceedings of the National Academy of Sciences 107 (12), 5411-5416, 2010 | 250 | 2010 |
| Inhibition of acetylcholinesterase, β-amyloid aggregation, and NMDA receptors in Alzheimer’s disease: a promising direction for the multi-target-directed ligands gold rush M Rosini, E Simoni, M Bartolini, A Cavalli, L Ceccarini, N Pascu, ... Journal of medicinal chemistry 51 (15), 4381-4384, 2008 | 242 | 2008 |
| A small molecule targeting the multifactorial nature of Alzheimer's disease A Cavalli, ML Bolognesi, S Capsoni, V Andrisano, M Bartolini, E Margotti, ... ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 46, 3689-3692, 2007 | 236 | 2007 |
| Multitarget drug discovery and polypharmacology ML Bolognesi, A Cavalli ChemMedChem 11 (12), 1190-1192, 2016 | 228 | 2016 |
| A catalytically silent FAAH-1 variant drives anandamide transport in neurons J Fu, G Bottegoni, O Sasso, R Bertorelli, W Rocchia, M Masetti, A Guijarro, ... Nature neuroscience 15 (1), 64-69, 2012 | 224 | 2012 |
| SAR of 9-amino-1, 2, 3, 4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues M Recanatini, A Cavalli, F Belluti, L Piazzi, A Rampa, A Bisi, S Gobbi, ... Journal of medicinal chemistry 43 (10), 2007-2018, 2000 | 222 | 2000 |
| Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis F Altznauer, S Conus, A Cavalli, G Folkers, HU Simon Journal of Biological Chemistry 279 (7), 5947-5957, 2004 | 213 | 2004 |
| Single-molecule pulling simulations can discern active from inactive enzyme inhibitors F Colizzi, R Perozzo, L Scapozza, M Recanatini, A Cavalli Journal of the American Chemical Society 132 (21), 7361-7371, 2010 | 206 | 2010 |
| Structural basis of cis-and trans-combretastatin binding to tubulin R Gaspari, AE Prota, K Bargsten, A Cavalli, MO Steinmetz Chem 2 (1), 102-113, 2017 | 205 | 2017 |
| Organocatalytic asymmetric conjugate addition of 1, 3‐dicarbonyl compounds to maleimides G Bartoli, M Bosco, A Carlone, A Cavalli, M Locatelli, A Mazzanti, P Ricci, ... Angewandte Chemie 118 (30), 5088-5092, 2006 | 199 | 2006 |
