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Adam Courtney
Adam Courtney
Assistant Professor of Pharmacology, University of Michigan
Verified email at umich.edu - Homepage
Title
Cited by
Cited by
Year
TCR signaling: mechanisms of initiation and propagation
AH Courtney, WL Lo, A Weiss
Trends in biochemical sciences 43 (2), 108-123, 2018
6062018
Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation
AH Courtney, EB Puffer, JK Pontrello, ZQ Yang, LL Kiessling
Proceedings of the National Academy of Sciences 106 (8), 2500-2505, 2009
1552009
CD45 functions as a signaling gatekeeper in T cells
AH Courtney, AA Shvets, W Lu, G Griffante, M Mollenauer, V Horkova, ...
Science signaling 12 (604), eaaw8151, 2019
1462019
Multivalent antigens for promoting B and T cell activation
NR Bennett, DB Zwick, AH Courtney, LL Kiessling
ACS chemical biology 10 (8), 1817-1824, 2015
932015
A phosphosite within the SH2 domain of Lck regulates its activation by CD45
AH Courtney, JF Amacher, TA Kadlecek, MN Mollenauer, BB Au-Yeung, ...
Molecular cell 67 (3), 498-511. e6, 2017
702017
Spatial control of cell fate using synthetic surfaces to potentiate TGF-β signaling
L Li, JR Klim, R Derda, AH Courtney, LL Kiessling
Proceedings of the National Academy of Sciences 108 (29), 11745-11750, 2011
662011
Small molecule inhibition of Csk alters affinity recognition by T cells
BN Manz, YX Tan, AH Courtney, F Rutaganira, E Palmer, KM Shokat, ...
Elife 4, e08088, 2015
522015
Synthetic antigens reveal dynamics of BCR endocytosis during inhibitory signaling
AH Courtney, NR Bennett, DB Zwick, J Hudon, LL Kiessling
ACS chemical biology 9 (1), 202-210, 2014
302014
Small-Molecule-Modified Surfaces Engage Cells through the αvβ3 Integrin
JR Klim, AJ Fowler, AH Courtney, PJ Wrighton, RTC Sheridan, ML Wong, ...
ACS Chemical Biology 7 (3), 518-525, 2012
212012
Combined analysis of T cell activation and T cell-mediated cytotoxicity by imaging cytometry
MK Chanda, CE Shudde, TL Piper, Y Zheng, AH Courtney
Journal of immunological methods 506, 113290, 2022
22022
Screening and Characterization of Allosteric Small Molecules Targeting Bruton’s Tyrosine Kinase
LE Kueffer, DY Lin, N Amatya, J Serrenho, RE Joseph, AH Courtney, ...
Biochemistry 63 (1), 94-106, 2023
12023
An engineered viral protein rewires signaling pathways to overcome T cell suppression.
Y Zheng, Z Gu, C Shudde, T Piper, X Wang, G Aleck, J Zhou, M Chanda, ...
The Journal of Immunology 212 (1_Supplement), 1100_5719-1100_5719, 2024
2024
A STAT5 activator protects CD8+ T cells in immunosuppressive environments
CE Shudde, Z Gu, TL Piper, Y Zheng, AH Courtney
The Journal of Immunology 210 (Supplement_1), 154.17-154.17, 2023
2023
Uncovering the role of STAT5 in CD8+ T cell fate
MK Chanda, Z Gu, TL Piper, CE Shudde, AH Courtney
The Journal of Immunology 210 (Supplement_1), 239.21-239.21, 2023
2023
Enhanced cytotoxic CD8+ T cell (CTL) antigen recognition by LCK activation
Y Zheng, TL Piper, AH Courtney
The Journal of Immunology 208 (Supplement_1), 55.14-55.14, 2022
2022
Abstract A074: A Zap70-dependent negative feedback loop governs Lck activation by CD45
AH Courtney, TA Kadlecek, B Au-Yeung, A Weiss
Cancer Immunology Research 4 (11_Supplement), A074-A074, 2016
2016
Abstract B042: Regulation of Lck activity by a cryptic phosphosite
AH Courtney, HE Sjolin-Goodfellow, Q Ji, TA Kadlecek, AR Salomon, ...
Cancer Immunology Research 4 (1_Supplement), B042-B042, 2016
2016
Investigating mechanisms of B cell antigen recognition with synthetic multivalent ligands
NR Bennett, AH Courtney, DB Zwick, LL Kiessling
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013
2013
Synthetic Antigens: Mechanistic Probes of B Cell Activation
AH Courtney
University of Wisconsin--Madison, 2011
2011
Altering immune signaling in B cells through coreceptor recruitment with multivalent antigens
AH Courtney, LL Kiessling
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 239, 2010
2010
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