Michael Hanson
Michael Hanson
Director of Technology Frost Institute of Chemistry and Molecular Science
Verified email at
Cited by
Cited by
High-resolution crystal structure of an engineered human β2-adrenergic G protein–coupled receptor
V Cherezov, DM Rosenbaum, MA Hanson, SGF Rasmussen, FS Thian, ...
science 318 (5854), 1258-1265, 2007
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
VP Jaakola, MT Griffith, MA Hanson, V Cherezov, EYT Chien, JR Lane, ...
Science 322 (5905), 1211-1217, 2008
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
DM Rosenbaum, V Cherezov, MA Hanson, SGF Rasmussen, FS Thian, ...
science 318 (5854), 1266-1273, 2007
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist
EYT Chien, W Liu, Q Zhao, V Katritch, G Won Han, MA Hanson, L Shi, ...
Science 330 (6007), 1091-1095, 2010
A specific cholesterol binding site is established by the 2.8 ┼ structure of the human β2-adrenergic receptor
MA Hanson, V Cherezov, MT Griffith, CB Roth, VP Jaakola, EYT Chien, ...
Structure 16 (6), 897-905, 2008
Crystal structure of a lipid G protein–coupled receptor
MA Hanson, CB Roth, E Jo, MT Griffith, FL Scott, G Reinhart, H Desale, ...
Science 335 (6070), 851-855, 2012
Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling
MH Bracey, MA Hanson, KR Masuda, RC Stevens, BF Cravatt
Science 298 (5599), 1793-1796, 2002
Crystal structure of the human cannabinoid receptor CB1
T Hua, K Vemuri, M Pu, L Qu, GW Han, Y Wu, S Zhao, W Shui, S Li, ...
Cell 167 (3), 750-762. e14, 2016
Microscale fluorescent thermal stability assay for membrane proteins
AI Alexandrov, M Mileni, EYT Chien, MA Hanson, RC Stevens
Structure 16 (3), 351-359, 2008
Crystal structures of agonist-bound human cannabinoid receptor CB1
T Hua, K Vemuri, SP Nikas, RB Laprairie, Y Wu, L Qu, M Pu, A Korde, ...
Nature 547 (7664), 468-471, 2017
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors
E Chun, AA Thompson, W Liu, CB Roth, MT Griffith, V Katritch, J Kunken, ...
Structure 20 (6), 967-976, 2012
Discovery of new GPCR biology: one receptor structure at a time
MA Hanson, RC Stevens
Structure 17 (1), 8-14, 2009
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence
H Rosen, RC Stevens, M Hanson, E Roberts, MBA Oldstone
Annual review of biochemistry 82, 637-662, 2013
5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology
Y Peng, JD McCorvy, K Harps°e, K Lansu, S Yuan, P Popov, L Qu, M Pu, ...
Cell 172 (4), 719-730. e14, 2018
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators
G Song, D Yang, Y Wang, C De Graaf, Q Zhou, S Jiang, K Liu, X Cai, ...
Nature 546 (7657), 312-315, 2017
Structure of the full-length glucagon class B G-protein-coupled receptor
H Zhang, A Qiao, D Yang, L Yang, A Dai, C De Graaf, S Reedtz-Runge, ...
Nature 546 (7657), 259-264, 2017
Crystal structure of antagonist bound human lysophosphatidic acid receptor 1
JE Chrencik, CB Roth, M Terakado, H Kurata, R Omi, Y Kihara, ...
Cell 161 (7), 1633-1643, 2015
Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 ┼ resolution
MA Hanson, RC Stevens
Nature structural biology 7 (8), 687-692, 2000
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 Ám size X-ray synchrotron beam
V Cherezov, MA Hanson, MT Griffith, MC Hilgart, R Sanishvili, ...
Journal of The Royal Society Interface 6 (suppl_5), S587-S597, 2009
Stabilization of the human β2-adrenergic receptor TM4–TM3–TM5 helix interface by mutagenesis of Glu1223. 41, a critical residue in GPCR structure
CB Roth, MA Hanson, RC Stevens
Journal of molecular biology 376 (5), 1305-1319, 2008
The system can't perform the operation now. Try again later.
Articles 1–20