Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: one-year findings from the IVAN randomized trial U Chakravarthy, SP Harding, CA Rogers, SM Downes, AJ Lotery, ... Ophthalmology 119 (7), 1399-1411, 2012 | 964 | 2012 |
Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial RE MacLaren, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ... The Lancet 383 (9923), 1129-1137, 2014 | 906 | 2014 |
Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial U Chakravarthy, SP Harding, CA Rogers, SM Downes, AJ Lotery, ... The Lancet 382 (9900), 1258-1267, 2013 | 832 | 2013 |
Central serous chorioretinopathy: towards an evidence-based treatment guideline TJ Van Rijssen, EH Van Dijk, S Yzer, K Ohno-Matsui, JEE Keunen, ... Progress in retinal and eye research 73, 100770, 2019 | 400 | 2019 |
Half-dose photodynamic therapy versus high-density subthreshold micropulse laser treatment in patients with chronic central serous chorioretinopathy: the PLACE trial EHC van Dijk, S Fauser, MB Breukink, R Blanco-Garavito, ... Ophthalmology 125 (10), 1547-1555, 2018 | 292 | 2018 |
Hydroxychloroquine retinopathy IH Yusuf, S Sharma, R Luqmani, SM Downes Eye 31 (6), 828-845, 2017 | 290 | 2017 |
A mutation in guanylate cyclase activator 1A (GUCA1A) in an autosomal dominant cone dystrophy pedigree mapping to a new locus on chromosome 6p21. 1 AM Payne, SM Downes, DAR Bessant, R Taylor, GE Holder, MJ Warren, ... Human molecular genetics 7 (2), 273-277, 1998 | 262 | 1998 |
Visual acuity after retinal gene therapy for choroideremia TL Edwards, JK Jolly, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ... New England Journal of Medicine 374 (20), 1996-1998, 2016 | 227 | 2016 |
Incidence and natural history of proliferative sickle cell retinopathy: observations from a cohort study SM Downes, IR Hambleton, EL Chuang, N Lois, GR Serjeant, AC Bird Ophthalmology 112 (11), 1869-1875, 2005 | 227 | 2005 |
Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder AJ Abrams, RB Hufnagel, A Rebelo, C Zanna, N Patel, MA Gonzalez, ... Nature genetics 47 (8), 926-932, 2015 | 217 | 2015 |
Missense mutations in a retinal pigment epithelium protein, bestrophin-1, cause retinitis pigmentosa AE Davidson, ID Millar, JE Urquhart, R Burgess-Mullan, Y Shweikh, ... The American Journal of Human Genetics 85 (5), 581-592, 2009 | 207 | 2009 |
Comparison of two reference standards in validating two field mydriatic digital photography as a method of screening for diabetic retinopathy PH Scanlon, R Malhotra, RH Greenwood, SJ Aldington, C Foy, M Flatman, ... British journal of ophthalmology 87 (10), 1258-1263, 2003 | 195 | 2003 |
Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo … A Lotery, S Sivaprasad, A O'Connell, RA Harris, L Culliford, L Ellis, A Cree, ... The Lancet 395 (10220), 294-303, 2020 | 190 | 2020 |
Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia K Xue, JK Jolly, AR Barnard, A Rudenko, AP Salvetti, MI Patrício, ... Nature medicine 24 (10), 1507-1512, 2018 | 188 | 2018 |
Chronic central serous chorioretinopathy: long-term follow-up and vision-related quality of life MB Breukink, AJM Dingemans, AI den Hollander, JEE Keunen, ... Clinical Ophthalmology, 39-46, 2016 | 150 | 2016 |
Next-generation sequencing (NGS) as a diagnostic tool for retinal degeneration reveals a much higher detection rate in early-onset disease ME Shanks, SM Downes, RR Copley, S Lise, J Broxholme, KAZ Hudspith, ... European journal of human genetics 21 (3), 274-280, 2013 | 150 | 2013 |
RPGR mutation associated with retinitis pigmentosa, impaired hearing, and sinorespiratory infections I Zito, SM Downes, RJ Patel, ME Cheetham, ND Ebenezer, SA Jenkins, ... Journal of medical genetics 40 (8), 609-615, 2003 | 150 | 2003 |
Mutations in REEP6 cause autosomal-recessive retinitis pigmentosa G Arno, SA Agrawal, A Eblimit, J Bellingham, M Xu, F Wang, C Chakarova, ... The American Journal of Human Genetics 99 (6), 1305-1315, 2016 | 135 | 2016 |
Autosomal dominant cone and cone-rod dystrophy with mutations in the guanylate cyclase activator 1A gene-encoding guanylate cyclase activating protein-1 SM Downes, GE Holder, FW Fitzke, AM Payne, MJ Warren, ... Archives of ophthalmology 119 (1), 96-105, 2001 | 126 | 2001 |
Unravelling the genetics of inherited retinal dystrophies: Past, present and future S Broadgate, J Yu, SM Downes, S Halford Progress in retinal and eye research 59, 53-96, 2017 | 123 | 2017 |